7252-68-8

Basic information

• Product Name: 2-{[(2,4-dimethylphenyl)amino]methyl}-1H-isoindole-1,3(2H)-dione
• Synonyms: 1H-isoindole-1,3(2H)-dione, 2-[[(2,4-dimethylphenyl)amino]methyl]-; 2-[(2,4-dimethylanilino)methyl]isoindoline-1,3-dione; 2-[(2,4-Dimethyl-phenylamino)-methyl]-isoindole-1,3-dione
• CAS NO: 7252-68-8
• Molecular Formula: C₁₇H₁₆N₂O₂
• Molecular Weight: 280.3211
• Mol File: 7252-68-8.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 464.8°C at 760 mmHg
• Flash Point: 234.9°C
• Density: 1.273g/cm³
• Vapor Pressure: 8.14E-09mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: 2-{[(2,4-dimethylphenyl)amino]methyl}-1H-isoindole-1,3(2H)-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-{[(2,4-dimethylphenyl)amino]methyl}-1H-isoindole-1,3(2H)-dione(7252-68-8)
• EPA Substance Registry System: 2-{[(2,4-dimethylphenyl)amino]methyl}-1H-isoindole-1,3(2H)-dione(7252-68-8)

Safety Data

• Hazardous Substances Data: 7252-68-8(Hazardous Substances Data)

Usage

Origin

Synthetic derivative of glutamic acid

Initial Purpose

Developed as a sedative and anti-nausea drug

Reason for Withdrawal

Teratogenic effects leading to severe birth defects, including limb malformations, if taken during pregnancy

Repurposed Uses

Treatment of multiple myeloma and leprosy

Mechanism of Action

Modulates the immune system and inhibits the production of tumor necrosis factor-alpha (TNF-α)

Regulatory Status

Under strict regulations, available only through special programs to prevent use in pregnant women and reduce the risk of birth defects

Upstream product

• 136918-14-4 phthalimide 
• 50-00-0 formaldehyd 
• 95-68-1 2,4-Xylidine