725237-22-9

Basic information

• Product Name: 4-chloro-6-(3-methoxyphenylamino)-2-methylsulfanylpyrimidine-5-carbonitrile
• Synonyms: 4-chloro-6-(3-methoxyphenylamino)-2-methylsulfanylpyrimidine-5-carbonitrile
• CAS NO: 725237-22-9
• Molecular Weight: 306.776
• Mol File: 725237-22-9.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-chloro-6-(3-methoxyphenylamino)-2-methylsulfanylpyrimidine-5-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: 4-chloro-6-(3-methoxyphenylamino)-2-methylsulfanylpyrimidine-5-carbonitrile(725237-22-9)
• EPA Substance Registry System: 4-chloro-6-(3-methoxyphenylamino)-2-methylsulfanylpyrimidine-5-carbonitrile(725237-22-9)

Safety Data

• Hazardous Substances Data: 725237-22-9(Hazardous Substances Data)

Upstream product

• 536-90-3 m-Anisidine 
• 33097-13-1 4,6-dichloro-2-(methylthio)-5-pyrimidinecarbonitrile 

Downstream Products

• 725237-37-6 C₁₃H₁₃N₅OS 
• 1374157-90-0 (R)-2-(5-cyano-4-(4-methoxybenzyloxy)-6-(3-(methoxy)phenylamino)pyrimidin-2-ylamino)butanamide 

Relevant articles and documents

OXYPYRIMIDINES AS SYK MODULATORS

The present invention is directed to compounds of formula (I) and tautomers thereof or pharmaceutically acceptable salts, esters, and prodrugs thereof which arc inhibitor of Syk kinase. The present invention is also directed to intermediates used in making such compounds, the preparation of such a compound, pharmaceutical compositions containing such a compound, methods of inhibition Syk kinase activity, methods of inhibition the platelet aggregation, and methods to prevent or treat a number of conditions mediated at least in part by Syk kinase activity, such as undesired thrombosis and Non Hodgkin's Lymphoma.