725252-08-4

Basic information

• Product Name: (+)-(2R,5R,6R)-5-isopropyl-2-methyl-6-(3-indolyl)-2-vinylcyclohexanone
• Synonyms: (+)-(2R,5R,6R)-5-isopropyl-2-methyl-6-(3-indolyl)-2-vinylcyclohexanone
• CAS NO: 725252-08-4
• Molecular Weight: 293.409
• Mol File: 725252-08-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (+)-(2R,5R,6R)-5-isopropyl-2-methyl-6-(3-indolyl)-2-vinylcyclohexanone(CAS DataBase Reference)
• NIST Chemistry Reference: (+)-(2R,5R,6R)-5-isopropyl-2-methyl-6-(3-indolyl)-2-vinylcyclohexanone(725252-08-4)
• EPA Substance Registry System: (+)-(2R,5R,6R)-5-isopropyl-2-methyl-6-(3-indolyl)-2-vinylcyclohexanone(725252-08-4)

Safety Data

• Hazardous Substances Data: 725252-08-4(Hazardous Substances Data)

Upstream product

• 148249-36-9 3-bromo-1-(1,1,1-triisopropylsilyl)-1H-indole 
• 123191-00-4 1-(triisopropylsilyl)-1H-indole 
• 120-72-9 indole 
• 725252-07-3 (5R,6R)-6-(1H-indol-3-yl)-2-methyl-5-(prop-1-en-2-yl)cyclohex-2-enone 
• 6485-40-1 (R)-Carvone 

Relevant articles and documents

Enantiospecific total synthesis of the hapalindoles, fischerindoles, and welwitindolinones via a redox economic approach

Full details are provided for the total synthesis of several members of the hapalindole family of natural products, including hapalindole Q, 12-epi-hapalindole D, 12-epi-fischerindole U, 12-epi-fischerindole G, 12-epi-fischerindole I, and welwitindolinone

Synthesis and absolute configuration of (+)-hapalindole Q

The versatility of brominated camphor derivatives as six-membered-ring chiral building blocks in the synthesis of compounds of mixed biogenesis has been demonstrated in an eight-step synthesis of (+)-hapalindole Q from (+)-(1R)-9-bromocamphor in an overall 8% yield which confirms the absolute stereochemistry to be 10R, 11R, 12R, 15R.