72564-76-2

Basic information

• Product Name: 6-chloro-9-(2-chloro-6-fluorobenzyl) purine
• CAS NO: 72564-76-2
• Molecular Weight: 297.119
• Mol File: 72564-76-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 6-chloro-9-(2-chloro-6-fluorobenzyl) purine(CAS DataBase Reference)
• NIST Chemistry Reference: 6-chloro-9-(2-chloro-6-fluorobenzyl) purine(72564-76-2)
• EPA Substance Registry System: 6-chloro-9-(2-chloro-6-fluorobenzyl) purine(72564-76-2)

Safety Data

• Hazardous Substances Data: 72564-76-2(Hazardous Substances Data)

Upstream product

• 55779-18-5 9-(2-chloro-6-fluorobenzyl)adenine 
• 68220-26-8 2-(bromomethyl)-1-chloro-3-fluorobenzene 
• 87-42-3 6-chloro-7H-purine 
• 72564-77-3 9-(2-chloro-6-fluorobenzyl)purin-6(1H)-one 

Downstream Products

• 76099-84-8 9-(2-chloro-6-fluorobenzyl)-6-pentylaminopurine 
• 76099-80-4 9-(2-chloro-6-fluorobenzyl)-6-isopropylaminopurine 
• 70091-21-3 9-(2-chloro-6-fluorobenzyl)-6-methylaminopurine 
• 72564-87-5 9-(2-chloro-6-fluorobenzyl)-6-benzylaminopurine 
• 76099-76-8 9-(2-chloro-6-fluorobenzyl)-6-anilinopurine 
• 76099-79-1 9-(2-chloro-6-fluorobenzyl)-6-diethylaminopurine 
• 70091-23-5 9-(2-chloro-6-fluorobenzyl)-6-dimethylaminopurine 
• 76099-81-5 9-(2-chloro-6-fluorobenzyl)-6-dipropylaminopurine 
• 76099-82-6 9-(2-chloro-6-fluorobenzyl)-6-iso-butylaminopurine 
• 76099-83-7 9-(2-chloro-6-fluorobenzyl)-6-sec-butylaminopurine 

Relevant articles and documents

9-(2-fluorobenzyl)-6-(alkylamino)-9H-purines. A new class of anticonvulsant agents

Several substituted aryl and 6-alkylamino analogues of the anticonvulsant purine 9-(2-fluorobenzyl)-6-(methylamino)-9H-purine were synthesized and tested for anticonvulsant activity against maximal electroshock-induced seizures (MES) in rats. Derivatives with a second fluoro substituent in the 5- or 6-position of the aryl moiety were very active with ip ED50's that ranged from 2 to 4 mg/kg. Congeners in which the purine 6-substituent was varied among a number of alkylamino groups possessed potent activity against MES that was comparable to or several times better than phenytoin.