725717-42-0

Basic information

• Product Name: 5-(2-HYDROXY-BENZOYL)-2-OXO-1-THIAZOL-2-YL-1,2-DIHYDRO-PYRIDINE-3-CARBONITRILE
• Synonyms: 5-(2-HYDROXY-BENZOYL)-2-OXO-1-THIAZOL-2-YL-1,2-DIHYDRO-PYRIDINE-3-CARBONITRILE;5-(2-hydroxybenzoyl)-2-oxo-1-(1,3-thiazol-2-yl)pyridine-3-carbonitrile
• CAS NO: 725717-42-0
• Molecular Formula: C16H9N3O3S
• Molecular Weight: 323.33
• Mol File: 725717-42-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-(2-HYDROXY-BENZOYL)-2-OXO-1-THIAZOL-2-YL-1,2-DIHYDRO-PYRIDINE-3-CARBONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(2-HYDROXY-BENZOYL)-2-OXO-1-THIAZOL-2-YL-1,2-DIHYDRO-PYRIDINE-3-CARBONITRILE(725717-42-0)
• EPA Substance Registry System: 5-(2-HYDROXY-BENZOYL)-2-OXO-1-THIAZOL-2-YL-1,2-DIHYDRO-PYRIDINE-3-CARBONITRILE(725717-42-0)

Safety Data

• Hazardous Substances Data: 725717-42-0(Hazardous Substances Data)

Upstream product

• 90158-62-6 2-cyano-N-(thiazol-2-yl)-acetamide 
• 17422-74-1 3-Formylchromone 

Relevant articles and documents

3-Formylchromones in Guareschi synthesis of 5-(2-hydroxybenzoyl)-2- pyridones

A set of 5-(2-hydroxybenzoyl)-pyrid-2-ones, which are analogous to cardiotonic drugs such as milrinone, has been prepared in high yield by recyclization of 3-formylchromones with acetic acid amides having at the α-position an electron-withdrawing group. The best reaction conditions were found to be heating in DMF in the presence of Me3SiCl as a promoter and water scavenger.