72647-32-6Relevant articles and documents
Metal beta-lactamase inhibitor
-
Paragraph 0082-0087; 0088; 0116-0118, (2020/03/11)
The invention discloses application of a triazole compound, or a stereoisomer thereof, or a salt thereof, or a solvate thereof, represented by formula I in preparation of a metal beta-lactamase inhibitor drug, and belongs to the field of medicinal chemistry. The invention further discloses a preparation method of compounds, and a pharmaceutical composition comprising the compounds.
Synthesis and tuberculostatic activity of 1,3-thiazacycloalkyl[3,2-b]-1,2, 4-triazoles
Milczarska, Barbara,Foks, Henryk,Dobrzycka, Urszula,Zwolska, Zofia,Augustynowicz-Kopec, Ewa
, p. 2793 - 2799 (2007/10/03)
The 4-hydroxyalkyl-1,2,4-triazole-3-thiones cyclization allowed us to work out the effective method of 1,3-thiazacycloalkyl[3,2-b]-1,2,4-triazoles synthesis. Some of the compounds that were obtained were tested for their tuberculostatic activity. Copyrigh