7267-58-5

Basic information

• Product Name: 2-[(Carboxycarbonothioyl)amino]anisole
• Synonyms: [(2-Methoxyphenyl)amino](thioxo)acetic acid;2-[(Carboxycarbonothioyl)amino]anisole
• CAS NO: 7267-58-5
• Molecular Formula: C₉H₉NO₃S
• Molecular Weight: 211.23766
• Mol File: 7267-58-5.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-[(Carboxycarbonothioyl)amino]anisole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-[(Carboxycarbonothioyl)amino]anisole(7267-58-5)
• EPA Substance Registry System: 2-[(Carboxycarbonothioyl)amino]anisole(7267-58-5)

Safety Data

• Hazardous Substances Data: 7267-58-5(Hazardous Substances Data)

Usage

Compound type

Substituted anisole derivative

Functional group

Carboxycarbonothioylamino

Potential uses

Antifungal agent, corrosion inhibitor for steel and other metals, synthesis of other organic compounds

Availability of information

Limited

Need for further research

Yes

Upstream product

• 328961-25-7 2-(2-methoxy-phenylamino)-2-thioxo-acetamide 
• 90-04-0 2-methoxy-phenylamine 
• 113449-16-4 methyl 2-((2-methoxyphenyl)amino)-2-oxoacetate 

Relevant articles and documents

Inhibitors of fumarylacetoacetate hydrolase domain containing protein 1 (Fahd1)

FAH domain containing protein 1 (FAHD1) acts as oxaloacetate decarboxylase in mitochondria, contributing to the regulation of the tricarboxylic acid cycle. Guided by a high-resolution X-ray structure of FAHD1 liganded by oxalate, the enzymatic mechanism of substrate processing is analyzed in detail. Taking the chemical features of the FAHD1 substrate oxaloacetate into account, the potential inhibitor structures are deduced. The synthesis of drug-like scaffolds afforded first-generation FAHD1-inhibitors with activities in the low micromolar IC50 range. The investigations disclosed structures competing with the substrate for binding to the metal cofactor, as well as scaffolds, which may have a novel binding mode to FAHD1.