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72677-81-7

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72677-81-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 72677-81-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,2,6,7 and 7 respectively; the second part has 2 digits, 8 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 72677-81:
(7*7)+(6*2)+(5*6)+(4*7)+(3*7)+(2*8)+(1*1)=157
157 % 10 = 7
So 72677-81-7 is a valid CAS Registry Number.

72677-81-7Downstream Products

72677-81-7Relevant articles and documents

Optimization of 2-aminothiazole derivatives as CCR4 antagonists

Wang, Xuemei,Xu, Feng,Xu, Qingge,Mahmud, Hossen,Houze, Jonathan,Zhu, Liusheng,Akerman, Michelle,Tonn, George,Tang, Liang,McMaster, Brian E.,Dairaghi, Daniel J.,Schall, Thomas J.,Collins, Tassie L.,Medina, Julio C.

, p. 2800 - 2803 (2007/10/03)

A series of 2-aminothiazole-derived antagonists of the CCR4 receptor has been synthesized and their affinity for the receptor evaluated using a [125I]TARC (CCL17) displacement assay. Optimization of these compounds for potency and pharmacokinetic properties led to the discovery of potent, orally bioavailable antagonists.

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