727-95-7

Basic information

• Product Name: (1H-INDOL-3-YL)-M-TOLYL-METHANONE
• Synonyms: (1H-INDOL-3-YL)-M-TOLYL-METHANONE;3-(3-Methylbenzoyl)indole
• CAS NO: 727-95-7
• Molecular Formula: C₁₆H₁₃NO
• Molecular Weight: 235.28
• Mol File: 727-95-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: (1H-INDOL-3-YL)-M-TOLYL-METHANONE(CAS DataBase Reference)
• NIST Chemistry Reference: (1H-INDOL-3-YL)-M-TOLYL-METHANONE(727-95-7)
• EPA Substance Registry System: (1H-INDOL-3-YL)-M-TOLYL-METHANONE(727-95-7)

Safety Data

• Hazardous Substances Data: 727-95-7(Hazardous Substances Data)

Upstream product

• 120-72-9 indole 
• 620-22-4 3-Methylbenzonitrile 
• 61560-94-9 3-methylphenyloxoacetic acid 
• 1711-06-4 3-Methylbenzoyl chloride 

Relevant articles and documents

METHODS OF TREATING CANCER

The present disclosure relates to methods of treating cancer in a patient using a combination of an inhibitor of an immune checkpoint protein and an indole compound or its phosphate derivative.

INDOLE COMPOUNDS AND THEIR USE

The present disclosure relates to indole compounds and pharmaceutical compositions thereof, and their use in stimulating the immune system of patients in need thereof and in treating cancer.

Decarboxylative/decarbonylative C3-acylation of indoles: Via photocatalysis: A simple and efficient route to 3-acylindoles

A simple and efficient strategy for the preparation of 3-acylindoles via visible-light promoted C3-acylation of free (NH)- and N-substituted indoles with α-oxocarboxylic acids was developed. The reaction tolerates a wide range of functional groups, and the corresponding 3-acylindoles were obtained in high yields under mild conditions.