72734-76-0

Basic information

• Product Name: 4-acetylphenyl 2,2-dimethylpropanoate
• Synonyms: 4-Acetylphenyl pivalate; propanoic acid, 2,2-dimethyl-, 4-acetylphenyl ester
• CAS NO: 72734-76-0
• Molecular Formula: C₁₃H₁₆O₃
• Molecular Weight: 220.2643
• Mol File: 72734-76-0.mol
• Article Data: 11

Chemical Properties

• Boiling Point: 322.7°C at 760 mmHg
• Flash Point: 139.9°C
• Density: 1.058g/cm³
• Vapor Pressure: 0.000275mmHg at 25°C
• Refractive Index: 1.502
• CAS DataBase Reference: 4-acetylphenyl 2,2-dimethylpropanoate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-acetylphenyl 2,2-dimethylpropanoate(72734-76-0)
• EPA Substance Registry System: 4-acetylphenyl 2,2-dimethylpropanoate(72734-76-0)

Safety Data

• Hazardous Substances Data: 72734-76-0(Hazardous Substances Data)

Upstream product

• 3282-30-2 pivaloyl chloride 
• 99-93-4 4-Hydroxyacetophenone 
• 1352413-16-1 C₁₂H₁₃F₃O₅S 
• 1184-88-9 sodium pivalate 
• 99-90-1 para-bromoacetophenone 
• 75-98-9 Trimethylacetic acid 

Downstream Products

• 120226-55-3 N-pivaloyl-p-chlorophenylmethylamine 
• 120226-49-5 N-(4-methoxybenzyl)pivalamide 
• 26209-45-0 N-benzyl-2,2-dimethylpropanamide 
• 99-93-4 4-Hydroxyacetophenone 
• 92-91-1 biphenyl-4-acetaldehyde 
• 13021-18-6 1-(4'-methoxy-biphenyl-4-yl)-ethanone 
• 56800-17-0 4-acetylphenyl 4-methoxybenzoate 
• 106052-23-7 diisopropyl [4-(acetyl)phenyl]phosphonate 

Relevant articles and documents

Rhodium-Catalyzed Deoxygenation and Borylation of Ketones: A Combined Experimental and Theoretical Investigation

The rhodium-catalyzed deoxygenation and borylation of ketones with B2pin2 have been developed, leading to efficient formation of alkenes, vinylboronates, and vinyldiboronates. These reactions feature mild reaction conditions, a broad substrate scope, and excellent functional-group compatibility. Mechanistic studies support that the ketones initially undergo a Rh-catalyzed deoxygenation to give alkenes via boron enolate intermediates, and the subsequent Rh-catalyzed dehydrogenative borylation of alkenes leads to the formation of vinylboronates and diboration products, which is also supported by density functional theory calculations.

General Paradigm in Photoredox Nickel-Catalyzed Cross-Coupling Allows for Light-Free Access to Reactivity

Self-sustained NiI/III cycles are established as a potentially general paradigm in photoredox Ni-catalyzed carbon–heteroatom cross-coupling reactions through a strategy that allows us to recapitulate photoredox-like reactivity in the absence of light across a wide range of substrates in the amination, etherification, and esterification of aryl bromides, the latter of which has remained, hitherto, elusive under thermal Ni catalysis. Moreover, the accessibility of esterification in the absence of light is especially notable because previous mechanistic studies on this transformation under photoredox conditions have unanimously invoked energy-transfer-mediated pathways.

TRIPHENYLETHYLENE COMPOUNDS AND USES THEREOF

Triphenylethylene compounds as dual aromatase inhibitors and selective estrogen receptors modulators are described. Also described are methods for treating patients of breast cancers, and patients of breast cancer comorbid with osteoporosis, using the des