727375-10-2Relevant articles and documents
Quinol-4-ones as steroid A-ring mimetics in nonsteroidal dissociated glucocorticoid agonists
Regan, John,Lee, Thomas W.,Zindell, Renée M.,Bekkali, Younes,Bentzien, J?rg,Gilmore, Thomas,Hammach, Abdelhakim,Kirrane, Thomas M.,Kukulka, Alison J.,Kuzmich, Daniel,Nelson, Richard M.,Proudfoot, John R.,Ralph, Mark,Pelletier, Josephine,Souza, Donald,Zuvela-Jelaska, Lijiljana,Nabozny, Gerald,Thomson, David S.
, p. 7887 - 7896 (2006)
We report on the nuclear receptor binding affinities, cellular activities of transrepression and transactivation, and anti-inflammatory properties of a quinol-4-one and other A-ring mimetic containing nonsteroidal class of glucocorticoid agonists.