727678-34-4

Basic information

• Product Name: ethyl 2-acetylamino-2-cyano-3-(2-chlorophenyl)-5-oxo-5-phenylpentanoate
• Synonyms: ethyl 2-acetylamino-2-cyano-3-(2-chlorophenyl)-5-oxo-5-phenylpentanoate
• CAS NO: 727678-34-4
• Molecular Weight: 412.873
• Mol File: 727678-34-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 2-acetylamino-2-cyano-3-(2-chlorophenyl)-5-oxo-5-phenylpentanoate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 2-acetylamino-2-cyano-3-(2-chlorophenyl)-5-oxo-5-phenylpentanoate(727678-34-4)
• EPA Substance Registry System: ethyl 2-acetylamino-2-cyano-3-(2-chlorophenyl)-5-oxo-5-phenylpentanoate(727678-34-4)

Safety Data

• Hazardous Substances Data: 727678-34-4(Hazardous Substances Data)

Upstream product

• 22966-11-6 (2E)-3-(2-chlorophenyl)-1-phenylprop-2-en-1-one 
• 90877-70-6 ethyl 2-acetamido-2-cyanoacetate 
• 3849-21-6 ethyl cyanoglyoxylate-2-oxime 

Downstream Products

• 727678-57-1 ethyl 3-acetylamino-3,4-dihydro-4-(2-chlorophenyl)-6-phenyl-2(1H)pyridone-3-carboxylate 

Relevant articles and documents

A novel approach to 1,2-dihydro-2-oxo-3-pyridinecarboxylic ester via aromatization induced by deamidation

A novel approach was developed for the preparation of 4,6-disubstituted-1, 2-dihydro-2-oxo-3-pyridinecarboxylic ester in moderate to good yields. This route involves a reaction sequence of Michael addition, transformation to ene-lactam, and aromatization, featuring easily available material, variable substituents, and good functional compatibility.