727706-53-8

Basic information

• Product Name: C₁₇H₁₅N₃S
• Synonyms: C₁₇H₁₅N₃S
• CAS NO: 727706-53-8
• Molecular Weight: 293.392
• Mol File: 727706-53-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₇H₁₅N₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₇H₁₅N₃S(727706-53-8)
• EPA Substance Registry System: C₁₇H₁₅N₃S(727706-53-8)

Safety Data

• Hazardous Substances Data: 727706-53-8(Hazardous Substances Data)

Upstream product

• 1125-60-6 isoquinolin-5-ylamine 
• 622-78-6 Benzyl isothiocyanate 

Downstream Products

• 1255211-44-9 C₁₇H₁₃N₃S 

Relevant articles and documents

An expedient synthesis of novel 2-substituted thiazolo[4,5-f]isoquinolines/ quinolines and benzo[1,2-d:4,3-d']bisthiazoles and their potential as inhibitors of COX-1 and COX-2

An efficient, general synthesis of 2-substituted thiazolo[4,5-f] isoquinolines, thiazolo[4,5-f]-quinolines and benzo[1,2-d:4,3-d']bisthiazoles has been accomplished from 5-nitroisoquinoline/quinoline and 6-nitrobenzothiazole, respectively, and all the products have been thoroughly identified spectroscopically (IR, 1H and 13C NMR, LR/HR EI/FAB/ESI-MS). The synthesis of thiazolo[4,5-f]isoquinolines constitutes the first synthesis of this class of heteroarenes. Eighteen compounds, covering all three types, were screened for inhibition of COX-1 and COX-2, and some of them showed moderate activities. ARKAT-USA, Inc.