728-47-2Relevant articles and documents
Preparations of SF5- and CF3-substituted arenes utilizing the 7-oxabicyclo[2.2.1]hept-2-ene synthones
Ponomarenko, Maxim V.,Lummer, Katrin,Fokin, Andrey A.,Serguchev, Yurii A.,Bassil, Bassem S.,Roeschenthaler, Gerd-Volker
, p. 8103 - 8112 (2013/12/04)
The synthesis of SF5- and CF3-substituted benzenes and naphthalenes from various 7-oxanorbornene derivatives utilizing SF 5Cl and CF3I radical addition reactions, followed by dehydrohalogenation and aromatizatio
The Diels-Alder Route to Trifluoromethyl-Substituted Carbo- and Heterocycles
Schlosser, Manfred,Keller, Holger
, p. 1587 - 1590 (2007/10/02)
Starting with 1,1,1-trifluoroacetone, 3-(trifluoromethyl)-1-(trimethylsilyloxy)-1,3-butadiene (2) has been prepared as a mixture of (Z) and (E) isomers.The diene undergoes cycloaddition reactions with a variety of dienophiles affording trifluoromethyl-substituted carbocyclic and heterocyclic compounds 7-11 in yields ranging from moderate to good. - Keywords: Trifluoromethyl substituents / Carbocycles / Heterocycles / Diels-Alder reactions / Electron-rich/electron-poor diene