7284-37-9Relevant articles and documents
The effect of monosaccharides on self-assembly of benzenetricarboxamides
Wang, Jue,Qi, Wenjing,Chen, Guosong
supporting information, p. 587 - 591 (2019/01/04)
The interaction between monosaccharides exhibits an important role in the assembly of monosaccharide-containing molecules. In this work, three common monosaccharides, glucose, galactose and mannose, are employed to investigate the effect of monosaccharide on the self-assembly of benzenetricarboxamide (BTA) core-containing molecules. In the presence of monosaccharides, three benzenetricarboxamide derivatives aggregate into different ordered structures. When alanine linkers are introduced to these molecules between the core and the monosacchride, morphologies of three types of monosaccharide BTAs turned to disordered, meanwhile their structures become similar with the increase of the length of alanine linkers, indicating the disappearance of the monosaccharide effects.
Small molecule glycoconjugates with anticancer activity
Pastuch-Gawo?ek, Gabriela,Musio?, Marta,Malarz, Katarzyna,Serda, Maciej,Czaplinska, Barbara,Musiol, Robert,Mrozek-Wilczkiewicz, Anna
supporting information, p. 130 - 144 (2017/11/03)
Glycoconjugates are combinations of sugar moieties with organic compounds. Due to their biological resemblance, such structures often have properties that are desirable for drugs. In this study we designed and synthesised several glycoconjugates from smal
Preparation and evaluation of a molecular recognition bionic solid phase extraction column for separation of glucosides
Tang, Ping-Ping,Cai, Ji-Bao,Gao, Yun,Su, Qing-De
experimental part, p. 1248 - 1256 (2011/10/08)
Amolecular recognition bionic solid phase extraction (SPE) column for separation of glucosides has been prepared using a positively charged β-glucosylamidine as the ligand inwhich a glyconmoiety is connected via an N-glycoside linkage. β-Glucosylamidine, highly potent and selective inhibitors of β-glycosidase, is immobilized through a one-step synthesize procedure involving the addition of β-glucosylamine and 2-iminothiolane. HCl simultaneously to a matrix modified with maleimido groups via an appropriate spacer to give a molecular recognition absorbent for β-glucosides. N-octyl-β-D-glucopyranoside and β-D-galactopyranoside or α-D-mannopyranoside was directly chromatographed through the bionic chromatographic column, resulting in a much stronger retention of β-D-glucopyranoside than β-D-galactopyranoside and α-D-mannopyranoside. The retained glucopyranoside could only be eluted by glucose solution. This indicates that the binding of the glucoside was of specific nature that corresponds to the glycon substrate specificity of the glucoside. The ease of preparation and the selective nature of the molecular recognition bionic chromatography should promise a large-scale preparation of the molecular recognition adsorbent for the purification and removal of glucosides according to their glycon substrate specificity.