72850-77-2Relevant articles and documents
Syntheses and Reactions of 2-Halo-5-thiazolecarboxylates
Lee, Len F.,Schleppnik, Francis M.,Howe, Robert K.
, p. 1621 - 1630 (2007/10/02)
A variety of 2-halo-5-thiazolecarboxylates was prepared from substituted-3-aminoacrylates and 3-ketoesters.Selective reduction of 2-chloro-5-thiazolecarboxylates 4a, 4i and 4j with sodium borohydride in ethanol provided the corresponding 2-halo-5-thiazolemethanols 27 - 29.Nucleophilic displacement on methyl methanesulfonate (32c) occured selectivity at the 5-substituent to provide 2-chloro-4-(trifluoromethyl)-5-(heteroatom-substituted methyl)thiazoles 32d-f.
2,4-Disubstituted-5-thiazole-carboxylic acids and derivatives
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, (2008/06/13)
2,4-Disubstituted-5-thiazolecarboxylic acids and derivatives thereof have been found to reduce herbicidal injury of corn, rice and sorghum plants due to the application thereto of acetamide herbicides.
