72885-92-8

Basic information

• Product Name: 2-phenyl-2H-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one
• Synonyms: 2-phenyl-2H-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one
• CAS NO: 72885-92-8
• Molecular Weight: 267.311
• Mol File: 72885-92-8.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-phenyl-2H-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-phenyl-2H-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one(72885-92-8)
• EPA Substance Registry System: 2-phenyl-2H-benzo[4,5]imidazo[1,2-d][1,2,4]thiadiazol-3-one(72885-92-8)

Safety Data

• Hazardous Substances Data: 72885-92-8(Hazardous Substances Data)

Upstream product

• 72885-89-3 3-phenylimino-3H-benzimidazo<2,1-c><1,2,4>-dithiazole 
• 103-71-9 phenyl isocyanate 
• 87504-19-6 Benzo[4,5]imidazo[2,1-c][1,2,4]dithiazol-(3Z)-ylidene-propyl-amine 
• 85997-29-1 2-butylbenzimidazo<1,2-d><1,2,4>thiadiazol-3(2H)-one 
• 87504-25-4 N-(2-aminophenyl)-N'-phenylharnstoff 
• 1155-37-9 bis-benzimidazole disulfide 

Downstream Products

• 4922-04-7 2-phenoxy-1H-benzo[d]imidazole 
• 98154-77-9 13-p-tolylimino-13H-dibenzimidazo<2,1-b:1',2'-e><1,3,5>thiadiazine 
• 98154-80-4 Benzo[4,5]imidazo[2,1-c][1,2,4]dithiazol-(3Z)-ylidene-(4-chloro-phenyl)-amine 
• 98154-76-8 Benzo[4,5]imidazo[2,1-c][1,2,4]dithiazol-(3Z)-ylidene-p-tolyl-amine 
• 98154-62-2 2-(p-chlorophenoxy)benzimidazole 
• 51314-51-3 N-butyl-1H-benzo[d]imidazol-2-amine 
• 118795-48-5 1-(3-Methyl-benzo[4,5]imidazo[2,1-b]thiazol-2-yl)-ethanone; compound with 1,3-dihydro-benzoimidazole-2-thione 
• 83792-76-1 (1H-benzoimidazol-2-yl)-(cyclohexyl)-amine 
• 51290-77-8 2-(benzylthio)-1H-benzo[d]imidazole 
• 2360-29-4 2-(phenylsulfanyl)-1H-benzimidazole 
• 75080-14-7 2-isobutylmercapto-1H-benzimidazole 
• 72885-89-3 3-phenylimino-3H-benzimidazo<2,1-c><1,2,4>-dithiazole 

Relevant articles and documents

Proton pump inhibitors

Novel thiadiazole compounds are provided, which are effective as proton pumps inhibitors, useful in treating peptic ulcers by inhibition of the proton pump enzyme H+/K+-ATPase. The compounds are 3-substituted 1,2,4-thiadiazolo [4,5- alpha ]benzimidazole and 3-substituted imidazo[1,2-d]-1,2,4-thiadiazoles corresponding to the general formula: where X and Z either represent an optionally substituted benzene ring fused to the diazole nucleus, or represent a variety of independent chemical groupings (hydrogen, lower alkyl, halo, etc.) and Y is selected from a wide range, e.g. heterocyclics and carbonyl groups.

THIADIAZOLE COMPOUNDS USEFUL AS PROTON PUMP INHIBITORS

Novel thiadiazole compounds are provided, which are effective as proton pumps inhibitors, useful in treating peptic ulcers by inhibition of the proton pump enzyme H+/K+-ATPase. The compounds are 3-substituted 1,2,4-thiadiazolo [4,5-alpha] benzimidazole an

ACYLIERUNG VON HETEROCYCLEN MIT KOHLENSAEUREDERIVATEN-III; SYNTHESEN VON BENZIMIDAZOLO (1,2,4)THIADIAZOLINEN

The addition products of benzimidazolinethione and isocyanates are easily cyclized to benzimidazolo(1,2,4)thiadiazoline systems 4 by treatment with Br2/NEt3.The thio-analogues 9 were synthesized from 2-aminophenyl thioureas and thiophosgene followe