7291-87-4Relevant articles and documents
A Conformationally Defined 6-s-trans-Retinoic Acid Isomer: Synthesis, Chemopreventive Activity, and Toxicity
Vaezi, Michael F.,Alam, Muzaffar,Sani, Brahma P.,Rogers, Tina S.,Simpson-Herren, Linda,et al.
, p. 4499 - 4507 (2007/10/02)
A conformationally defined retinoic acid analog (1) which contains a dimethylene bridge to maintain the 6-s-trans orientation for two terminal double bonds in the polyene chain was synthesized.A Reformatsky reaction was utilized to extend the polyene chai