72952-51-3

Basic information

• Product Name: Propanamide, N-[2-[(2-benzoyl-4-chlorophenyl)methylamino]-2-oxoethyl]-2-methyl-
• CAS NO: 72952-51-3
• Molecular Formula: C20H21ClN2O3
• Molecular Weight: 372.851
• Mol File: 72952-51-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Propanamide, N-[2-[(2-benzoyl-4-chlorophenyl)methylamino]-2-oxoethyl]-2-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanamide, N-[2-[(2-benzoyl-4-chlorophenyl)methylamino]-2-oxoethyl]-2-methyl-(72952-51-3)
• EPA Substance Registry System: Propanamide, N-[2-[(2-benzoyl-4-chlorophenyl)methylamino]-2-oxoethyl]-2-methyl-(72952-51-3)

Safety Data

• Hazardous Substances Data: 72952-51-3(Hazardous Substances Data)

Upstream product

• 1022-13-5 5-chloro-2-(methylamino)benzophenone 
• 14529-12-5 6-chloro-N-methylisatoic anhydride 
• 72952-53-5 5-chloro-2-(methylamino)hippuric acid 
• 54888-03-8 5-chloro-2-(aceturoylmethylamino)benzophenone 
• 4743-17-3 5-Chloroisatoic anhydride 
• 72952-50-2 4-isobutyroyl-7-chloro-1-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione 
• 5973-28-4 7-chloro-1-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione 
• 72952-52-4 potassium 5-chloro-2-(methylamino)hippurate 

Relevant articles and documents

New Synthesis of Diazepam

An efficient preparation of 7-chloro-1-methyl-3,4-dihydro-1H-1,4-benzodiazepine-2,5-dione from 5-chloro-N-methylisatoic anhydride and glycine has been devised, and from it, by the action of phenylmagnesium chloride on its N-acetyl-derivative followed by treatment with hydroxylamine and cleavage of the resulting desacetyl oxime with sodium bisulfite, diazepam has been synthesized.The overall yield is about 50percent from 5-chloroisatoic anhydride.