72959-94-5

Basic information

• Product Name: Propanoic acid, 2-fluoro-, ethyl ester, (R)-
• Synonyms: (R)-2-Fluoro-propionic acid ethyl ester;(+)-(R)-Ethyl 2-fluorpropionat;(R)-(+)-ethyl 2-fluoropropionate;(R)-2-fluoropropanoic acid ethyl ester;(R)-2-fluoropropionic acid ethyl ester;ethyl 2-(R)-fluoropropanoate
• CAS NO: 72959-94-5
• Molecular Formula: C5H9FO2
• Molecular Weight: 120.12200
• Mol File: 72959-94-5.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: Propanoic acid, 2-fluoro-, ethyl ester, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Propanoic acid, 2-fluoro-, ethyl ester, (R)-(72959-94-5)
• EPA Substance Registry System: Propanoic acid, 2-fluoro-, ethyl ester, (R)-(72959-94-5)

Safety Data

• Hazardous Substances Data: 72959-94-5(Hazardous Substances Data)

Upstream product

• 687-47-8 (S)-Ethyl lactate 
• 685-88-1 fluoromalonic acid diethyl ester 
• 102712-70-9 (R)-2-Fluoro-3-(toluene-4-sulfonyloxy)-propionic acid ethyl ester 
• 63696-99-1 (S)-ethyl 2-(methylsulfonyloxy)propanoate 
• 94721-39-8 (R)-(+)-2-fluoro-2-methylmalonic acid monoethyl ester 
• 102712-69-6 (R)-(+)-ethyl 3-hydroxy-2-fluoropropionate 

Downstream Products

• 876747-18-1 (2R)-2-fluoropropanol 

Relevant articles and documents

Synthesis of the optically pure monoethyl ester of (R)-(+)-2-fluoromalonic acid by use of immobilized lipase-my for asymmetric hydrolysis

A synthetic approach to optically pure (+)-2-fluoromalonic acid monoethyl ester was based on the enantiotopic specificity of asymmetric hydrolysis by an immobilized enzyme. The absolute configuration of monoethyl (+)-2-fluoromalonate was determined : it is the (R)-enantiomer.

PROCESS FOR PRODUCING -SUBSTITUTED ESTER

There is provided a process for producing an α-substituted ester by reaction of a fluorosulfuric acid ester of α-hydroxyester with a Grignard reagent in the presence of a zinc catalyst. It is newly found that the reaction for production of α-substituted e

PROCESS FOR THE MANUFACTURE OF FLUORINATED COMPOUNDS

A process for the manufacture of a fluorinated organic compound of formula R-F wherein R is an organic residue, which comprises reacting a starting material of general formula R-X wherein X is a leaving group with SO2F2. Addition of