72985-00-3

Basic information

• Product Name: 3,5'-Bis(brommethyl)-2'-methyldeoxybenzoin trimethylene dithioketal
• CAS NO: 72985-00-3
• Molecular Weight: 486.335
• Mol File: 72985-00-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3,5'-Bis(brommethyl)-2'-methyldeoxybenzoin trimethylene dithioketal(CAS DataBase Reference)
• NIST Chemistry Reference: 3,5'-Bis(brommethyl)-2'-methyldeoxybenzoin trimethylene dithioketal(72985-00-3)
• EPA Substance Registry System: 3,5'-Bis(brommethyl)-2'-methyldeoxybenzoin trimethylene dithioketal(72985-00-3)

Safety Data

• Hazardous Substances Data: 72985-00-3(Hazardous Substances Data)

Upstream product

• 626-15-3 1,3-bis-(bromomethyl)benzene 
• 72985-28-5 3,5'-Bis(methoxymethyl)-2'-methyldeoxybenzoin trimethylene dithioketal 
• 72984-98-6 3,5'-Bis(methoxymethyl)-2'-methyldeoxybenzoin 
• 73502-06-4 m-(Methoxymethyl)benzaldehyde trimethylene dithioacetal 
• 72985-25-2 Methyl-5-(methoxymethyl)-2-methylbenzoate 
• 72985-24-1 methyl 5-(hydroxymethyl )-2-methylbenzoate 
• 72985-21-8 5-(hydroxymethyl)-2-methylbenzoic acid 
• 125604-03-7 1-(bromomethyl)-3-(methoxymethyl)benzene 
• 28746-20-5 3-(methoxymethyl)benzaldehyde 
• 72985-27-4 5-(Methoxymethyl)-2-methylbenzyl bromide 
• 109-80-8 1.3-propanedithiol 
• 72984-99-7 3,5'-Bis(bromomethyl)-2'-methyldeoxybenzoin 

Relevant articles and documents

Microbial Stereodifferentiating Reduction of (+/-)4-Methyl- and (+/-)-6-Methyl-1-oxometacyclophanes and Revision of the Absolute Configuration of 4-Substituted Metacyclophanes

Partial oxidative hydrolysis of 4-bromo-1,1,10,10-bis(trimethylenedithio)metacyclophane (7) yielded the bromo ketones 8 and 9 which were respectively converted into (+/-)-4-methyl- (3) and (+/-)-6-methyl-1-oxometacyclophanes (4).The unambiguous synthesis of (+/-)-3 from 2,5-dimethylbenzoic acid (18) assigned their structures.Incubation of (+/-)-3 with Rhodotorula rubra gave a mixture of (-)-ketone 3, (-) axial alcohol 38, and (-) equatorial alcohol 39.The observed (-) Cotton effect indicated the pS configuration of (-)-3, and transformation of (-)-3 into (+)-4-methylmetacyclophane (5) permitted the assignment of the pR configuration to (+)-5, opposite to Schloegl's proposal.This conclusion was further supported by the parallel sequence of the steps starting from (+/-)-6-methyl ketone.