730-18-7

Basic information

• Product Name: Carbamic acid, (phenylmethoxy)-, phenyl ester
• CAS NO: 730-18-7
• Molecular Formula: C14H13NO3
• Molecular Weight: 243.262
• Mol File: 730-18-7.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Carbamic acid, (phenylmethoxy)-, phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Carbamic acid, (phenylmethoxy)-, phenyl ester(730-18-7)
• EPA Substance Registry System: Carbamic acid, (phenylmethoxy)-, phenyl ester(730-18-7)

Safety Data

• Hazardous Substances Data: 730-18-7(Hazardous Substances Data)

Upstream product

• 100-44-7 benzyl chloride 
• 2687-43-6 O-benzylhydoxylamine hydrochloride 
• 501-53-1 benzyl chloroformate 
• 622-33-3 N-benzyloxyamine 
• 1885-14-9 phenyl chloroformate 

Downstream Products

• 95705-20-7 1,3,5-tribenzyloxy-1,3,5-triazine-2,4,6(1H,3H,5H)-trione 
• 81505-57-9 C₃₆H₃₈N₂O₇ 

Relevant articles and documents

Catalytic substitution/cyclization sequences of: O -substituted Isocyanates: Synthesis of 1-alkoxybenzimidazolones and 1-alkoxy-3,4-dihydroquinazolin-2(1 H)-ones

O-Substituted isocyanates (O-isocyanates) have rarely been used in organic synthesis, given their tendency to undergo side reactions (e.g., trimerization). Herein, we show that masked (blocked) O-isocyanate precursors allow one-pot or cascade reaction sequences featuring base-catalyzed substitution with 2-iodoanilines and 2-iodobenzylamines followed by copper-catalyzed cyclization, to form benzimidazolones and 3,4-dihydroquinazolin-2(1H)-ones. This work shows that O-isocyanates can serve as efficient building blocks for the synthesis of hydroxylamine-containing heterocycles.