73040-60-5

Basic information

• Product Name: NSC 176404
• Synonyms: 5-(4-Bromophenyl)thiazol-2-amine;NSC 176404;5-(4-bromophenyl)-2-Thiazolamine;5-(4-Bromo-phenyl)-thiazol-2-ylamine
• CAS NO: 73040-60-5
• Molecular Formula: C₉H₇BrN₂S
• Molecular Weight: 255.13428
• Mol File: 73040-60-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 205-206 ºC
• Boiling Point: 410.9 °C at 760 mmHg
• Flash Point: 202.3 °C
• Appearance: /
• Density: 1.636
• CAS DataBase Reference: NSC 176404(CAS DataBase Reference)
• NIST Chemistry Reference: NSC 176404(73040-60-5)
• EPA Substance Registry System: NSC 176404(73040-60-5)

Safety Data

• Hazardous Substances Data: 73040-60-5(Hazardous Substances Data)

Usage

General Description

NSC 176404, also known as 4-Acetoxyphenylacetic acid, is a chemical compound that has been studied for its potential therapeutic effects. It is an acetic acid derivative and a phenol ether. NSC 176404 has been investigated for its anti-inflammatory and hepatoprotective properties. Research has shown that NSC 176404 may have the potential to protect against liver damage caused by various toxic substances and to reduce inflammation. However, further research is needed to fully understand its mechanisms of action and potential applications in medicine.

Upstream product

• 61693-77-4 1-(p-bromophenyl)-2,2-dichloroethanol 
• 17356-08-0 thiourea 
• 4654-39-1 4-bromophenethanol 
• 27200-79-9 p-bromophenylacetaldehyde 
• 1122-91-4 4-bromo-benzaldehyde 

Downstream Products

• 73040-61-6 N-[5-(4-bromo-phenyl)-thiazol-2-yl]-acetamide 

Relevant articles and documents

FE NANOPARTICLES WITH PPM CONTENTS OF PD, CU AND/OR NI, REACTIONS IN WATER CATALYZED BY THEM

The present application discloses a nanoparticle composition prepared from a mixture comprising: a) a transition metal salt; b) an iron salt; and c) a reducing agent; and methods for the use of such compositions, including the reduction of an organic compound comprising a nitro group to form an organic compound comprising an amine group, the Cu-catalyzed cyclization of an azide and an alkyne (click chemistry) and cross coupling reactions, notably Suzuki-Miyaura reactions. The transition metal salts are in particular Pd, Cu and Ni salts, the content of these metals being typically in the ppm range based on the major constituent Fe in the final products.

Safe and Selective Nitro Group Reductions Catalyzed by Sustainable and Recyclable Fe/ppm Pd Nanoparticles in Water at Room Temperature

As a result of a unique synergy between ligand-free Fe/ppm Pd nanoparticles and PEG-containing designer surfactants, a facile and selective reduction of nitro-containing aromatics and heteroaromatics can be effected in water at room temperature in the presence of NaBH4. This new nanotechnology involves low catalyst loadings, is highly chemoselective, and tolerates a wide variety of functional groups. The process, which includes recycling of the entire aqueous medium, offers a general, environmentally responsible, and notably safe approach to highly valued reductions of nitro-containing compounds.