73108-75-5

Basic information

• Product Name: 2H-1-Benzopyran-2-one, 6-phenyl-
• CAS NO: 73108-75-5
• Molecular Formula: C15H10O2
• Molecular Weight: 222.243
• Mol File: 73108-75-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-2-one, 6-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-2-one, 6-phenyl-(73108-75-5)
• EPA Substance Registry System: 2H-1-Benzopyran-2-one, 6-phenyl-(73108-75-5)

Safety Data

• Hazardous Substances Data: 73108-75-5(Hazardous Substances Data)

Upstream product

• 82119-79-7 6-phenylchromone-3-carboxylic acid 
• 115560-72-0 3-Hydroxy-3-(4-methoxymethoxy-biphenyl-3-yl)-N,N-dimethyl-propionamide 
• 92-69-3 4-Phenylphenol 
• 115590-28-8 2-(methoxymethoxy)-5-phenylbenzaldehyde 
• 1761-63-3 2-hydroxy-5-phenylbenzaldehyde 
• 927-80-0 1-ethoxyacetylene 
• 471-25-0 Propiolic acid 
• 141-32-2 acrylic acid n-butyl ester 
• 4894-75-1 1-phenyl-4-cyclohexanone 
• 138116-09-3 2-O-acetyl-4-bromosalicylaldehyde 
• 19063-55-9 6-bromo-2H-chromen-2-one 
• 24388-23-6 2-phenyl-4,4,5,5-tetramethyl-1,3,2-dioxoborole 
• 1761-61-1 5-bromosalicyclaldehyde 
• 54098-94-1 dimethylphenylborane 

Downstream Products

• 1063714-27-1 ethyl 2-amino-4-(2-oxo-2-(piperidin-1-yl)ethyl)-6-phenyl-4Hchromene-3-carboxylate 
• 1063714-28-2 ethyl 2-amino-4-(2-morpholino-2-oxoethyl)-6-phenyl-4H-chromene-3-carboxylate 
• 1063714-30-6 ethyl 2-amino-4-(2-oxo-2-(piperazin-1-yl)ethyl)-6-phenyl-4Hchromene-3-carboxylate 
• 1033753-87-5 ethyl 2-amino-4-(2-ethoxy-2-oxoethyl)-6-phenyl-4H-chromene-3-carboxylate 
• 1063714-82-8 ethyl 2-(2-amino-3-cyano-6-phenyl-4H-chromen-4-yl)acetate 
• 1063714-25-9 isopropyl 2-amino-4-(2-isopropoxy-2-oxoethyl)-6-phenyl-4Hchromene-3-carboxylate 
• 1063714-32-8 ethyl 2-amino-4-(2-(diethylamino)-2-oxoethyl)-6-phenyl-4H-chromene-3-carboxylate 

Relevant articles and documents

Practical, Large-Scale Preparation of Benzoxepines and Coumarins through Rhodium(III)-Catalyzed C-H Activation/Annulation Reactions

Herein we disclose the assembly of benzoxepines and coumarins from 2-alkenylphenol precursors using [Cp*RhCl2]2 as the precatalyst and alkynes or carbon monoxide as reacting partners. The preparation of benzoxepines and coumarins can be scaled up to 33 mmol using low catalyst loadings.

Process for preparing coumarin derivatives using phenol and propiolic acid

Provided is a manufacturing method of coumarin derivative. The manufacturing method of coumarin derivative comprises a step of making a phenol compound react with a propiolic acid compound. According to the present invention, the manufacturing method of coumarin derivative is quick and efficient, and is useful to fields requiring synthesis of coumarin derivatives of various structures.COPYRIGHT KIPO 2016

Tandem aldehyde-alkyne-amine coupling/cycloisomerization: A new synthesis of coumarins

Cu-catalyzed A3 coupling of ethoxyacetylene, pyrrolidine and salicylaldehydes led to a concomitant cycloisomerization followed by hydrolysis of the resultant vinyl ether to afford coumarins in a cascade process. The reaction proceeded through exclusive 6-endo-dig cyclization and is compatible with halo and keto groups giving coumarins in good to moderate yields.