73127-51-2Relevant articles and documents
A convergent stereocontrolled synthesis of [3-14C]solanesol
Roe, Stephen J.,Oldfield, Mark F.,Geach, Neil,Baxter, Andrew
, p. 485 - 491 (2014/03/21)
In this communication, we report the synthesis of 5 mCi of [3- 14C]solanesol (1) prepared from ethyl [3-14C]acetoacetate and (all-E)-octaprenyl bromide (2) in four steps, with a specific radioactivity of 19.83 mCi/mmol and with a chemical/ stereochemical and radiochemical purity of ≥ 95%. (Figure 1). Position 3 of the chain was selected for 14C labelling because of the metabolic stability of this position. Unlabelled (all-E)-octaprenyl (18) (Scheme 4) necessary for this work was prepared via a convergent iterative 'allyl-allyl' coupling approach of precursors easily derived from readily available inexpensive starting materials. Copyright
Polyene alcohol derivative and process for producing the same
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, (2008/06/13)
There is disclosed a novel polyene alcohol derivative of the formula [I]: wherein, R represents a hydrogen atom or a protective group for a hydroxy group, and Y represents the following group: wherein, R represents a hydrogen atom or a protective group for a hydroxy group, and Y represents the following group, and a production method thereof.