73148-98-8Relevant articles and documents
Synthesis of substance-P C-terminal hexapeptide analogues and their biological activity. Analogues with antagonistic activity without containing D-amino acids
Karagiannis,Manopoulou,Poulos,Stavropoulos
, p. 667 - 673 (2007/10/02)
Analogues of the C-terminal hexapeptide of substance P have been synthesized in which each amino-acid residue was replaced by the bulky and strong lipophilic residue Asp(OBzl). The amino-acid residue of other selected places has also been replaced by Glu(
DEHYDROPHENYLALANINE ANALOGS OF 6-11 FRAGMENT OF SUBSTANCE P
Wasiak, Tadeusz,Koziolkiewicz, Wiktor
, p. 861 - 865 (2007/10/02)
Two dehydro analogs of 6-11 fragment of Substance P: p-Glu-Phe-Δ Phe-Gly-Leu-MetNH2 and p-Glu-Δ Phe-Phe-Gly-Leu-MetNH2 have been synthesized by solution methodology.Both compounds are biologically active on blood pressure in rats.
Model Studies on Papain-Catalyzed Peptide Synthesis in a Biphasic Aqueous-Organic System
Doering, Guenter,Kuhl, Peter,Jakubke, Hans-Dieter
, p. 1165 - 1174 (2007/10/02)
Several model peptides have been synthesized enzymatically using papain as a catalyst in biphasic aqueous-organic systems.The effect of different cosolvents, pH, buffer concentration, and reaction time on the papain-catalyzed synthesis was examined.A comp