73168-78-2

Basic information

• Product Name: N-(3,4-methylenedioxyphenethyl)-3-benzyloxy-4-methoxyphenylacetic acid amide
• CAS NO: 73168-78-2
• Molecular Weight: 419.477
• Mol File: 73168-78-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(3,4-methylenedioxyphenethyl)-3-benzyloxy-4-methoxyphenylacetic acid amide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(3,4-methylenedioxyphenethyl)-3-benzyloxy-4-methoxyphenylacetic acid amide(73168-78-2)
• EPA Substance Registry System: N-(3,4-methylenedioxyphenethyl)-3-benzyloxy-4-methoxyphenylacetic acid amide(73168-78-2)

Safety Data

• Hazardous Substances Data: 73168-78-2(Hazardous Substances Data)

Upstream product

• 5487-33-2 O-benzylhomoisovanillic acid 
• 1484-85-1 3,4-methylenedioxyphenylethylamine 
• 54313-33-6 2-(3-(benzyloxy)-4-methoxyphenyl)acetyl chloride 

Downstream Products

• 73180-40-2 11-benzyloxy-10-methoxy-5,8,13,13a-tetrahydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline 
• 155137-67-0 5-(3-Benzyloxy-4-methoxy-benzyl)-6-propyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline 
• 155137-66-9 5-(3-Benzyloxy-4-methoxy-benzyl)-6-ethyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline 
• 108017-85-2 5-(3-benzyloxy-4-methoxy-benzyl)-6-methyl-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline 
• 109741-34-6 (+/-)-1-(3-hydroxy-4-methoxybenzyl)-1,2,3,4-tetrahydro-2-methyl-6,7-methylenedioxyisoquinoline 
• 62926-26-5 1-(3-benzyloxy-4-methoxybenzyl)-6,7-methylenedioxy-3,4-dihydroisoquinoline 
• 103046-40-8 5-(3-benzyloxy-4-methoxy-benzyl)-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]isoquinoline 

Relevant articles and documents

Synthesis of some 1-(3-hydroxy-4-methoxybenzyl)-2-alkyl-6,7-methylenedioxy-1,2,3,4-tetrahydroisoquinolines and their binding affinities to DA receptor subtypes

1-(3-hydroxy-4-methoxybenzyl)-2-alkyl-6,7-methylenedioxytetrahydroisoquinolines (3a-c), derived from the D1 selective antagonist S-bulbocapnine by cleavage of the bond between the 2 aromatic moieties, have been synthesized and their in vitro affinity towards D1 and D2 receptors evaluated.Of the compounds tested, the 2-methyl derivative 3a while showing poor affinity towards D1 receptors was able to inhibit the D2 radioligand 3H-raclopride binding by 60percent at 10-5 M.Conformational analysis allows reasonable explanations of the loss of D1-affinity of 3a with respect to the model. substituted 1-(3-hydroxy-4-methoxybenzyl)-6,7-methylenedioxytetrahydroisoquinoline / D1 and D2 receptor binding / bulbocapnine conformational analysis