73177-66-9Relevant articles and documents
Regioselective Sulfonylvinylation of the Unactivated C(sp3)-H Bond via a C-Centered Radical-Mediated Hydrogen Atom Transfer (HAT) Process
Yang, Shan,Wu, Xinxin,Wu, Shuo,Zhu, Chen
, p. 4837 - 4841 (2019)
Given the similarity of multiple sp3 C-H bonds in electronic properties and bond dissociation energy (BDE), regioselective sp3 C-H bond functionalization remains a paramount challenge. Here, we report a C-centered radical-mediated approach for site-specific sulfonylvinylation of the C(sp3)-H bond via the hydrogen atom transfer (HAT) process. The reaction features mild conditions, broad substrate scope, and high regioselectivity and stereoselectivity, manifesting the nontrivial synthetic potential.
2,2-Dimethylcyclopropyl 4-methylphenyl ketone as a SET probe
Timberlake, Jack W.,Chen, Tonghua
, p. 6043 - 6046 (2007/10/02)
2,2-Dimethylcyclopropyl 4-methylphenyl ketone in the presence of Sml2 and DMPU is a good SET probe. The ortho positions of the aromatic ring provide a good source to trap the newly formed tertiary radical.