731851-94-8

Basic information

• Product Name: 10-methoxy-dibenzo[b,f]azepine-5-carboxylic acid phenyl ester
• Synonyms: 10-methoxy-dibenzo[b,f]azepine-5-carboxylic acid phenyl ester
• CAS NO: 731851-94-8
• Molecular Weight: 343.382
• Mol File: 731851-94-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 10-methoxy-dibenzo[b,f]azepine-5-carboxylic acid phenyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 10-methoxy-dibenzo[b,f]azepine-5-carboxylic acid phenyl ester(731851-94-8)
• EPA Substance Registry System: 10-methoxy-dibenzo[b,f]azepine-5-carboxylic acid phenyl ester(731851-94-8)

Safety Data

• Hazardous Substances Data: 731851-94-8(Hazardous Substances Data)

Upstream product

• 149-73-5 trimethyl orthoformate 

Downstream Products

• 28721-09-7 10-methoxy-5H-dibenz[b,f]azepine-5-carboxamide 
• 28721-07-5 oxcarbazepine 
• 4698-11-7 10-methoxy-5H-dibenzo[b,f]azepine 

Relevant articles and documents

A new synthesis of oxcarbazepine using a Friedel-Crafts cyclization strategy

A novel, simple, and straightforward process for the large-scale synthesis of oxcarbazepine, the active ingredient of Trileptal, a medicine for the treatment of epilepsy, has been developed. Starting from readily available 1,3-dihydro-1-phenyl-2H-indol-2-one, a Friedel-Crafts cyclization strategy provides a direct route to the tricyclic framework of the target molecule. Crucial to the success of the strategy was the choice of the proper nitrogen-protecting group.