732-68-3Relevant articles and documents
A new class of metal-free catalysts for direct diastereo- and regioselective Mannich reactions in aqueous media
Wu, Yin-Su,Cai, Jiwen,Hu, Zhi-Ya,Lin, Guang-Xin
, p. 8949 - 8952 (2004)
Camphor sulfonic acid and three sulfonated amino acids shows to efficiently catalyze direct Mannich reactions of benzaldehyde, aniline and various ketones in aqueous media, with high diastereo- or regioselectivities. Camphor sulfonic acid is an efficient catalyst for Mannich reactions of benzaldehyde, aniline and various ketones in aqueous media, with diastereo- or regioselectivities. Meanwhile, three sulfonated amino acids can catalyze the same type of reactions effectively with high diastereo- or regioselectivities.
Diastereoselective three-component Mannich reaction catalyzed by silica-supported ferric hydrogensulfate
Eshghi, Hossein,Rahimizadeh, Mohammad,Hosseini, Mohsen,Javadian-Saraf, Aida
, p. 197 - 203 (2013/07/27)
A highly anti-diastereoselective three-component Mannich reaction of aromatic amines and aromatic aldehydes with cyclohexanone in the presence of silica-supported ferric hydrogensulfate has been developed. The best selectivity was obtained where there were electron-donating groups on both aldehyde and amine. Selectivity decreases when electron-withdrawing groups are present on the aldehyde; in these cases selectivity is improved if an electron-donating group is present on the amine.
Silica-supported boric acid with ionic liquid: A novel recyclable catalytic system for one-pot three-component mannich reaction
Kumar, Vishal,Sharma, Upendra,Verma, Praveen Kumar,Kumar, Neeraj,Singh, Bikram
experimental part, p. 639 - 645 (2011/07/06)
A rapid and efficient silica-supported boric acid/ionic liquid ([β-mim][PF6]), catalyzed, one-pot three-component Mannich reaction has been carried out to synthesize b-amino carbonyl compounds at room temperature. The reaction afforded desired
