73217-31-9

Basic information

• Product Name: 3-(CHLOROMETHYL)-5-(4-METHOXYPHENYL)-1,2,4-OXADIAZOLE
• Synonyms: 3-(CHLOROMETHYL)-5-(4-METHOXYPHENYL)-1,2,4-OXADIAZOLE
• CAS NO: 73217-31-9
• Molecular Formula: C₁₀H₉ClN₂O₂
• Molecular Weight: 224.64
• Mol File: 73217-31-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 62-64°C
• Boiling Point: 354.9°C at 760 mmHg
• Flash Point: 168.4°C
• Appearance: /
• Density: 1.278g/cm³
• Vapor Pressure: 6.63E-05mmHg at 25°C
• Refractive Index: 1.547
• CAS DataBase Reference: 3-(CHLOROMETHYL)-5-(4-METHOXYPHENYL)-1,2,4-OXADIAZOLE(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(CHLOROMETHYL)-5-(4-METHOXYPHENYL)-1,2,4-OXADIAZOLE(73217-31-9)
• EPA Substance Registry System: 3-(CHLOROMETHYL)-5-(4-METHOXYPHENYL)-1,2,4-OXADIAZOLE(73217-31-9)

Safety Data

• Hazard Codes: C,Xn
• Statements: 36/37/38-41-37/38-22
• Safety Statements: 26-36/37/39-39
• Hazardous Substances Data: 73217-31-9(Hazardous Substances Data)

Usage

General Description

3-(Chloromethyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole is a chemical compound with the molecular formula C10H9ClN2O2. It is a derivative of 1,2,4-oxadiazole and contains a chloromethyl group and a 4-methoxyphenyl group. 3-(CHLOROMETHYL)-5-(4-METHOXYPHENYL)-1,2,4-OXADIAZOLE has potential applications in the field of medicinal chemistry and pharmaceutical research, as it exhibits biological activities that are being studied for potential therapeutic uses. Additionally, it may also be used in the synthesis of other organic compounds and as a building block for the creation of new materials with specific properties. The chemical and physical properties of 3-(chloromethyl)-5-(4-methoxyphenyl)-1,2,4-oxadiazole make it a versatile and potentially valuable compound for various scientific and industrial applications.

InChI:InChI=1/C10H9ClN2O2/c1-14-8-4-2-7(3-5-8)10-12-9(6-11)13-15-10/h2-5H,6H2,1H3

Upstream product

• 255876-60-9 C₁₀H₁₁ClN₂O₃ 
• 100-07-2 4-methoxy-benzoyl chloride 

Downstream Products

• 73217-43-3 1-[5-(4-methoxy-phenyl)-[1,2,4]oxadiazol-3-ylmethyl]-pyridinium; chloride 
• 73235-62-8 N'-[5-(4-methoxy-phenyl)-[1,2,4]oxadiazol-3-ylmethylene]-N,N-dimethyl-benzene-1,4-diamine N'-oxide 

Relevant articles and documents

ALKALOID AMINOESTER DERIVATIVES AND MEDICINAL COMPOSITION THEREOF

The present invention relates to alkaloid aminoester derivatives acting as muscarinic receptor antagonists, processes for their preparation, compositions comprising them and therapeutic uses thereof.

The discovery of a selective, high affinity A2B adenosine receptor antagonist for the potential treatment of asthma

Adenosine has been suggested to play a role in asthma, possibly via activation of A2B adenosine receptors on mast cells and other pulmonary cells. We describe our initial efforts to discover a xanthine based selective A2B AdoR antagonist that resulted in the discovery of CVT-5440, a high affinity A2B AdoR antagonist with good selectivity (A2B AdoR Ki = 50 nM, selectivity A1 > 200: A2A > 200: A3 > 167).