73225-13-5

Basic information

• Product Name: 3-methyl-4-nitro-1-p-nitrophenylpyrazole
• Synonyms: 3-methyl-4-nitro-1-p-nitrophenylpyrazole
• CAS NO: 73225-13-5
• Molecular Weight: 248.198
• Mol File: 73225-13-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 3-methyl-4-nitro-1-p-nitrophenylpyrazole(CAS DataBase Reference)
• NIST Chemistry Reference: 3-methyl-4-nitro-1-p-nitrophenylpyrazole(73225-13-5)
• EPA Substance Registry System: 3-methyl-4-nitro-1-p-nitrophenylpyrazole(73225-13-5)

Safety Data

• Hazardous Substances Data: 73225-13-5(Hazardous Substances Data)

Upstream product

• 7539-22-2 3-methyl-1-(4-nitrophenyl)-1H-pyrazole 
• 90946-24-0 3-methyl-4-nitro-1-phenyl-1H-pyrazole 
• 1128-54-7 3-methyl-1-phenyl-1H-pyrazole 
• 100-16-3 4-nitrophenylhydrazone 

Downstream Products

• 119071-43-1 3-Methyl-4-nitro-1-(4-nitrophenyl)-5-(tosylmethyl)pyrazol 
• 90916-84-0 4-(3-methyl-4-nitro-pyrazol-1-yl)-aniline 

Relevant articles and documents

THE NITRATION OF SOME PHENYL-SUBSTITUTED N-HETEROCYCLES

The nitration of 3-methyl-1-phenylpyrazole using nitric acid and sulfuric acid at 0 deg C gives the p-nitrophenyl isomer as the only isolated mono nitro-product and 3-methyl-4-nitro-1-p-nitrophenylpyrazole as the dinitro-product. 3-Methyl-4-phenylpyrazole gives 3-methyl-4-p-nitrophenylpyrazole with the second nitration also occurring in the phenyl ring to give 3-methyl-4-(2',4'-dinitrophenyl)pyrazole. 2-Phenylimidazole nitrates under these conditions to give first 2-p-nitrophenylimidazole and then 4-nitro-2-p-nitrophenylimidazole whilst 4-phenylimidazole gives 4-nitro-5-p-nitrophenylimidazole readily even when the amount of nitric acid is limited to one equivalent and only traces of a mono nitro-product are found. 2-Phenylimidazoline gives solely the m-nitrophenyl isomer under the same conditions.The mixed acid nitration at 0 deg C of 4-phenylmorpholine gives 4-m-nitrophenyl- and 4-p-nitrophenylmorpholine in the ratio of about 5:1.