73226-77-4Relevant articles and documents
ANTI-FUNGAL TREATMENT
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, (2018/03/25)
Provided are compounds, methods, and pharmaceutical compositions useful for treatment of fungal infections, e.g., aspergillosis, candidiasis, cryptococcosis, histoplasmosis, and the like. For example, the pharmaceutical composition may include a pharmaceutically acceptable carrier or excipient, and a compound represented by Ar— C(=NR1)NR2— A---X— Y— Het2 and pharmaceutically acceptable salts thereof. Ar may be an optionally substituted aryl or nitrogen- containing heteroaryl. R1 and R2 may independently be H, optionally substituted C1-C6 aikyi, or optionally substituted C3-C6 cyeloalkyi. A may be a bond or an optionally substituted linking moiety comprising 1, 2, or 3 rings. Each ring in the optionally substituted linking moiety may independently be one of: aryl, cyeloalkyi, heterocycloalkyl, and heteroaryl. X may be O, S, amide, or a bond. Y may be optionally substituted C1-C10 alkyi or optionally substituted C2-C10 alkenyl. Het2 may be an optionally substituted five-membered nitrogen-containing heteroaromatic ring comprising 1, 2, or 3 ring heteroatoms.
BROMINATION OF ARYLFURANS
Oleinik, A.F.,Solov'eva, N.P.,Turchin, K.F.,Sheinker, Yu.N.,Novitskii, K.Yu.,et al.
, p. 334 - 338 (2007/10/02)
The bromination of 2-arylfurans has been studied.The structures of the compounds obtained have been determined with the aid of NMR spectra.
