732306-18-2Relevant articles and documents
Synthesis of chiral iridium complexes immobilized on amphiphilic polymers and their application to asymmetric catalysis
Itsuno, Shinichi,Hashimoto, Yosuke,Haraguchi, Naoki
, p. 3037 - 3044 (2014)
This article details the enantioselective catalytic performance of crosslinked, polymer immobilized, Ir-based, chiral complexes for transfer hydrogenation of cyclic imines to chiral amines. Polymerization of the achiral vinyl monomer, divinylbenzene, and
Asymmetric transfer hydrogenation of aromatic ketones in water using a polymer-supported chiral catalyst containing a hydrophilic pendant group
Arakawa, Yukihiro,Chiba, Atsuko,Haraguchi, Naoki,Itsuno, Shinichi
supporting information; experimental part, p. 2295 - 2304 (2009/10/08)
Hydrophilic polymers having pendant groups of carboxylates or sulfonates have been used as a polymer support for chiral 1,2-diamine monosulfonamides. The polymeric chiral complex prepared from the polymer-supported chiral ligand with ruthenium dichloride·p-cymene was used in the asymmetric transfer hydrogenation of prochiral ketones in water. The balance between hydrophilicity and hydrophobicity of the polymer support influenced both the reactivity and the enantioselectivity of the reaction in water. The chiral polymeric complex having a quaternary ammonium salt structure as the pendant group worked well in water. In most cases the polymer-supported catalyst having a quaternary ammonium sulfonate pendant group showed superior enantioselectivity compared to the corresponding non-supported model catalyst in the solution system. The polymeric catalysts can be reused without loss of catalytic activity.
