7334-82-9Relevant articles and documents
ENZYME ACTIVATED SELF-IMMOLATIVE N-SUBSTITUTED NITROGEN MUSTARD PRODRUGS
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Page 65, (2008/06/13)
This invention pertains to certain enzyme (CPG2) activated self-immolative nitrogen mustard prodrugs, which are useful in enzyme prodrug therapy (EPT), such as ADEPT and GDEPT, for the treatment of proliferative conditions, such as cancer, and which have
A NEW SYNTHESIS OF AROMATIC AND HETEROAROMATIC NITROGEN MUSTARDS VIA 3-PYRROLINES
Palmer, Brian D,Denny, William A
, p. 601 - 610 (2007/10/02)
Reaction of aromatic and heteroaromatic halides with 3-pyrroline gives adducts which can be converted in a three-step process to nitrogen mustards.