73424-43-8

Basic information

• Product Name: 1-(4-Fluorphenyl)-2-phenyl-1-ethanon-p-tolylsulfonylhydrazon
• Synonyms: 1-(4-Fluorphenyl)-2-phenyl-1-ethanon-p-tolylsulfonylhydrazon
• CAS NO: 73424-43-8
• Molecular Weight: 382.458
• Mol File: 73424-43-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1-(4-Fluorphenyl)-2-phenyl-1-ethanon-p-tolylsulfonylhydrazon(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(4-Fluorphenyl)-2-phenyl-1-ethanon-p-tolylsulfonylhydrazon(73424-43-8)
• EPA Substance Registry System: 1-(4-Fluorphenyl)-2-phenyl-1-ethanon-p-tolylsulfonylhydrazon(73424-43-8)

Safety Data

• Hazardous Substances Data: 73424-43-8(Hazardous Substances Data)

Upstream product

• 347-84-2 1-(4-fluorophenyl)-2-phenylethanone 
• 1576-35-8 toluene-4-sulfonic acid hydrazide 
• 462-06-6 fluorobenzene 
• 103-80-0 phenylacetyl chloride 

Downstream Products

• 73424-52-9 4-(4-Fluorphenyl)-5-phenyl-1,2,3-thiadiazol 

Relevant articles and documents

Copper-catalyzed radical reaction of N -tosylhydrazones: Stereoselective synthesis of (E)-vinyl sulfones

A new chemistry of hydrazines that is a copper-catalyzed radical reaction to synthesize vinyl sulfones from readily available N-tosylhydrazones has been described. The protocol provides a novel strategy for the synthesis of various vinyl sulfones including α, β-disubstituted ones and terminal ones. The advantages of the transformation include excellent E stereoselectivity, broad substrate scope, low cost of reagents, and convenient operation. A novel and efficient one-pot synthesis of alkynes from N-tosylhydrazones has been achieved. The studies provide important complementary approaches for the syntheses of vinyl sulfones and alkynes.