73425-20-4Relevant articles and documents
Synthesis of Tetrahydrothiopyrano[2,3-b]indole [60]Fullerene Derivatives via Hetero-Diels–Alder Reaction of C60 and α,β-Unsaturated Indole-2-thiones
Matloubi Moghaddam, Firouz,Ghanbari, Bahram,Behzadi, Masoumeh,Baghersad, Mohammad Hadi
, p. 911 - 915 (2017/03/27)
Hetero-Diels–Alder reactions of [60]fullerene with α,β-unsaturated thio-oxindoles (3a, 3b, 3c), prepared from thio-oxindole 1 and heteroaromatic aldehydes (2a, 2b, 2c), to generate tetrahydrothiopyrano[2,3-b]indole [60]fullerene cycloadducts (5a, 5b, 5c) under thermal or microwave irradiation were described. The yields were improved, and the reaction time was decreased by conducting the reaction under microwave irradiation.
Highly efficient synthesis of thieno[2,3-b]indole derivatives
Boeini, Hassan Zali
experimental part, p. 1268 - 1272 (2009/10/16)
Thieno[2,3-b]indole derivatives were efficiently prepared via the reaction of 1,3-dihydro-2H-indole-2-thiones with α-bromo-substituted ketones or aldehydes and in the presence of Et3N (Scheme 2 and Table). The reaction took place under very mil
Tetrahydrothiopyrano[2,3-b]indole derivatives
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, (2008/06/13)
Tetrahydrothiopyrano[2,3-b]indole derivative represented by the formula I: STR1 wherein R1 is hydrogen, alkyl, hydroxyalkyl, alkenyl, aralkyl, aryl, --COR5 (wherein R5 is alkyl, alkenyl, aryl or alkoxy) or STR2 (wherein Y is alkylene, oxoalkylene, hydroxyalkylene and R6 and R7 are each hydrogen or alkyl): R2 is hydrogen or alkyl; R3 is hydrogen, alkyl, hydroxyalkyl, alkenyl, aralkyl, aryl or dialkylaminoalkyl or STR3 is pyrrolidino, piperidino, piperazino, 4-alkylpiperazino, 4-arylpiperazino or morpholino; R4 is hydrogen or alkyl; A is methylene, alkylmethylene, ethylene, alkylethylene; X is hydrogen or one or two groups selected from the group consisting of halogen, alkyl, alkoxy, hydroxy and halogenoalkyl; and n is an integer of 0 to 2 and its pharmaceutically acceptacle salts; synthesized from 2-propargylthioindole or 2-(4-hydroxy-2-butynylthio)-indole; useful as analgesic and anti-inflammatory agent.