7347-28-6Relevant articles and documents
Efficient catalytic aryl amination of bromoarenes using 3-iminophosphine palladium(II) chloride
Samblanet, Danielle C.,Schmidt, Joseph A. R.
supporting information, p. 7 - 18,12 (2012/12/12)
While pursuing the development of new hydroamination catalysts, a 3-iminophosphine palladium(II) chloride complex [(3IP)PdCl2] was synthesized that has subsequently proven to be an effective precatalyst for the aryl amination of bromoarenes. This (3IP)PdCl2 complex has been utilized in the catalytic aryl amination of both bromobenzene and bromopyridine derivatives, specifically yielding excellent activity in coupling reactions involving bromobenzene, 4-bromotoluene, and 2-bromopyridine. Using a standard set of catalytic conditions, many alkyl and aryl amines have been investigated as coupling partners in the aryl amination of bromoarenes. In general, secondary alkyl amines and ortho-substituted anilines proved to be the best substrates for this reaction, commonly giving quantitative conversion to products, while primary amines and other anilines gave only poor to moderate results. Catalytic screening data, product yields, and full characterization of isolated products are included.
The anionic thia-Fries rearrangement of aryl triflates
Charmant, Jonathan P. H.,Dyke, Alan M.,Lloyd-Jones, Guy C.
, p. 380 - 381 (2007/10/03)
Aryl triflates undergo LDA-mediated rearrangement to generate o-hydroxyaryl trifluoromethylsulfones. In some cases, partitioning between rearrangement and aryne generation can be controlled.