73477-53-9 Usage
Description
ALPHA-GUANIDINOGLUTARIC ACID (GGA) is a naturally occurring compound that acts as a linear mixed-type inhibitor of neuronal nitric oxide synthase (nNOS) with an inhibition constant (Ki) of 2.69 μM. It is typically found in small quantities in the cerebral cortex of cats, and its levels increase following a seizure event. GGA's unique properties make it a potential candidate for various applications in different industries.
Uses
Used in Pharmaceutical Industry:
ALPHA-GUANIDINOGLUTARIC ACID is used as a research compound for understanding its inhibitory effects on nNOS. Its presence in the cerebral cortex and increased levels after seizures suggest that GGA may play a role in neurological processes and could be a target for therapeutic interventions in conditions related to nitric oxide dysregulation.
Used in Neurological Research:
ALPHA-GUANIDINOGLUTARIC ACID is used as a biomarker for studying seizure activity in cats. The increase in GGA levels following a seizure indicates its potential use in monitoring and understanding the underlying mechanisms of seizure disorders, which could lead to the development of novel treatment strategies.
Used in Drug Development:
ALPHA-GUANIDINOGLUTARIC ACID is used as a lead compound in the development of new drugs targeting nNOS. Its inhibitory properties make it a promising starting point for designing drugs that could potentially treat conditions associated with excessive nitric oxide production, such as neurodegenerative diseases, inflammation, and certain types of cancer.
Check Digit Verification of cas no
The CAS Registry Mumber 73477-53-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,4,7 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 73477-53:
(7*7)+(6*3)+(5*4)+(4*7)+(3*7)+(2*5)+(1*3)=149
149 % 10 = 9
So 73477-53-9 is a valid CAS Registry Number.
