73532-83-9 Usage
Type
Synthetic derivative
Parent drug
Cytarabine (antiviral and anticancer drug)
Ester composition
Cytarabine and stearylphosphate
Purpose
To increase lipophilicity
Effect on cellular uptake
Improved
Impact on pharmacological properties
Enhanced
Addition of stearylphosphate moiety
Facilitates penetration through cell membranes
Result of modification
Enhanced intracellular accumulation
Efficacy
Greater
Selectivity
Improved
Potential applications
Treatment of various viral infections and cancers
Structure
Combination of an arabinofuranosylcytosine base with a stearylphosphate group attached to the 5' position of the cytosine sugar moiety.
Check Digit Verification of cas no
The CAS Registry Mumber 73532-83-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,3,5,3 and 2 respectively; the second part has 2 digits, 8 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 73532-83:
(7*7)+(6*3)+(5*5)+(4*3)+(3*2)+(2*8)+(1*3)=129
129 % 10 = 9
So 73532-83-9 is a valid CAS Registry Number.
InChI:InChI=1/C27H50N3O8P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20-36-39(34,35)37-21-22-24(31)25(32)26(38-22)30-19-18-23(28)29-27(30)33/h18-19,22,24-26,31-32H,2-17,20-21H2,1H3,(H,34,35)(H2,28,29,33)/t22-,24-,25+,26?/m1/s1
73532-83-9Relevant articles and documents
Treatments for flaviviridae virus infection
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Page/Page column 27, (2008/06/13)
The present invention provides methods for treating infections, in a host, by viruses belonging to the Flaviviridae family, such as HCV, comprising administering an Ara-C homologue to the host.
