73550-85-3Relevant articles and documents
Synthesis and activity of azaterphenyl diamidines against Trypanosoma brucei rhodesiense and Plasmodium falciparum
Hu, Laixing,Arafa, Reem K.,Ismail, Mohamed A.,Patel, Alpa,Munde, Manoj,Wilson, W. David,Wenzler, Tanja,Brun, Reto,Boykin, David W.
experimental part, p. 6651 - 6658 (2009/12/24)
A series of azaterphenyl diamidines has been synthesized and evaluated for in vitro antiprotozoal activity against both Trypanosoma brucei rhodesiense (T. b. r.) and Plasmodium falciparum (P. f.) and in vivo efficacy in the STIB900 acute mouse model for T
Synthesis and Antitrypanosomal Activity of Some Bis(4-guanylphenyl) Five- and Six-Membered Ring Heterocycles
Das, Bijan P.,Wallace, Rebecca A.,Boykin, David Withers
, p. 578 - 581 (2007/10/02)
2,5-Bis(4-guanylphenyl)-1,3-oxazole, 2,5-bis(4-guanylphenyl)-1,3,4-oxadiazole and -1,3,4-thiadiazole, and 3,6-bis(4-guanylphenyl)pyridazine and several of their ''cyclic guanyl'' analogues have been synthesized. 2,5-Bis(4-guanylphenyl)-1,3-oxazole and -1,