73553-21-6

Basic information

• Product Name: (4-methylbenzyl)(pent-4-en-1-yl)sulfane
• Synonyms: (4-methylbenzyl)(pent-4-en-1-yl)sulfane
• CAS NO: 73553-21-6
• Molecular Weight: 206.352
• Mol File: 73553-21-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (4-methylbenzyl)(pent-4-en-1-yl)sulfane(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methylbenzyl)(pent-4-en-1-yl)sulfane(73553-21-6)
• EPA Substance Registry System: (4-methylbenzyl)(pent-4-en-1-yl)sulfane(73553-21-6)

Safety Data

• Hazardous Substances Data: 73553-21-6(Hazardous Substances Data)

Upstream product

• 4498-99-1 4-methylbenzylthiol 
• 1119-51-3 bromopentene 
• 104-81-4 4-Methylbenzyl bromide 
• 72209-88-2 S-(4-methylbenzyl)isothiouronium bromide 

Downstream Products

• 14310-20-4 4-methylbibenzyl 

Relevant articles and documents

Thioether-Directed NiH-Catalyzed Remote γ-C(sp3)-H Hydroamidation of Alkenes by 1,4,2-Dioxazol-5-ones

A NiH-catalyzed thioether-directed cyclometalation strategy is developed to enable remote methylene C-H bond amidation of unactivated alkenes. Due to the preference for five-membered nickelacycle formation, the chain-walking isomerization initiated by the NiH insertion to an alkene can be terminated at the γ-methylene site remote from the alkene moiety. By employing 2,9-dibutyl-1,10-phenanthroline as the ligand and dioxazolones as the reagent, the amidation occurs at the γ-C(sp3)-H bonds to afford the amide products in up to 90% yield (>40 examples) with remarkable regioselectivity (up to 24:1 rr).