73557-48-9

Basic information

• Product Name: 1-(1,1-difluoro-2-propenyl)cyclohexanol
• Synonyms: 1-(1,1-difluoro-2-propenyl)cyclohexanol
• CAS NO: 73557-48-9
• Molecular Weight: 176.206
• Mol File: 73557-48-9.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 1-(1,1-difluoro-2-propenyl)cyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,1-difluoro-2-propenyl)cyclohexanol(73557-48-9)
• EPA Substance Registry System: 1-(1,1-difluoro-2-propenyl)cyclohexanol(73557-48-9)

Safety Data

• Hazardous Substances Data: 73557-48-9(Hazardous Substances Data)

Upstream product

• 460-25-3 1,1-difluoro-1,3-dibromopropane 
• 108-94-1 cyclohexanone 
• 420-90-6 3-bromo-3,3-difluropropene 

Relevant articles and documents

Gem-Difluoroallylation of Aldehydes and Ketones as a Convenient Route to α,α-Difluorohomoallylic Alcohols

In the presence of zinc, 3-bromo-3,3-difluoropropene or 3-iodo-1,1-difluoropropene reacted with carbonyl compounds to give the corresponding α,α-difluorohomoallylic alcohols in good yields at 0 deg C to room temperature.The reaction is applicable to aliph

gem-(DIFLUOROALLYL)LITHIUM: PREPARATION BY LITHIUM-HALOGEN EXCHANGE AND UTILIZATION IN ORGANOSILICON AND ORGANIC SYNTHESIS.

gem-(Difluoroallyl)lithium may be generated by lithium-bromine exchange between n-butyllithium and CH//2 equals CHCF//2Br at minus 95 degree C by using an in situ procedure. When this preparation is carried out in the presence of chlorosilanes, aldehydes, ketones, and esters, products are formed, often in good yield. The factors determining the regioselectivity in addition to C equals O of unsymmetrically substituted allylic lithium reagents are discussed.