7357-41-7

Basic information

• Product Name: 3-{[3-(chlorosulfonyl)phenyl]sulfonyl}benzenesulfonyl chloride
• Synonyms: 3-{[3-(chlorosulfonyl)phenyl]sulfonyl}benzenesulfonyl chloride
• CAS NO: 7357-41-7
• Molecular Formula: C₁₂H₈Cl₂O₆S₃
• Molecular Weight: 415.29
• Mol File: 7357-41-7.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-{[3-(chlorosulfonyl)phenyl]sulfonyl}benzenesulfonyl chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{[3-(chlorosulfonyl)phenyl]sulfonyl}benzenesulfonyl chloride(7357-41-7)
• EPA Substance Registry System: 3-{[3-(chlorosulfonyl)phenyl]sulfonyl}benzenesulfonyl chloride(7357-41-7)

Safety Data

• Hazardous Substances Data: 7357-41-7(Hazardous Substances Data)

Usage

Uses

Diphenyl Sulfone-3,3''-disulfonyl Chloride is the derivative of 4,4’-Dichlorodiphenyl Sulfone (D434165), which is an antibacterial used in the treatment of dermatitis herpetiformis.

Upstream product

• 71-43-2 benzene 
• 127-63-9 diphenyl sulphone 

Downstream Products

• 300382-89-2 C₂₆H₂₄N₂O₆S₃ 
• 911065-84-4 C₂₀H₂₈N₂O₆S₃ 
• 300405-44-1 3,3'-sulfonyl-bis-benzenesulfonic acid dianilide 
• 1111058-61-7 3,3'-bis(2-phenylprop-2-en-1-ylsulfonyl)diphenyl sulfone 

Relevant articles and documents

Synthesis of biologically active of some novel sulphonamides

CONTROLLED chlorosulponation of diphenylsulphone (1), thiaxanthone (2) and benzophenone (3) with chlorosulphonic acid yielded diphenylsulphone-3,3′- disulphonyl-chloride (4a), thiaxanthone-3,3′- disulphonylchloride (5) and benzophenone -3,3′-di

CHLOROSULFONATION OF SOME DIPHENYL DERIVATIVES

Benzophenone (1), diphenyl sulfone, and 4-nitro-2'-chloro- and 4-nitro-2',6'-dichlorophenyl ethers (23,24) have been chlorosulfonated.The direct yield of benzophenone-3,3'-disulfonyl chloride (2) was low, the majority of product was the disulfonic acid.Diphenyl sulfone (11) with a large amount of chlorosulfonic acid (8 mols) at 140 deg gave the 3,3'-disulfonyl chloride (12).With less reagent (6 mols) at 90 deg a mixture of the 3-sulfonyl chloride (21) and diphenyl sulfone was formed.Subsequent reaction with sodium azide gave the 3-sulfonyl azide (22).The diphenyl ether sulfonyl chlorides (25,26) were very susceptible to hydrolysis, especially (26) which probably accounts for the low yield obtained (31percent).The various sulfonyl chlorides were characterized as amides, azides, hydrazides and hydrazones (Tables I-III) and their i.r., n.m.r., and mass spectral data are included.