73579-08-5

Basic information

• Product Name: 1-Methyl-4-(methylamino)piperidine
• Synonyms: 1-METHYL-4-(METHYLAMINO)PIPERIDINE, 96;RANEY 2800 NICKEL, ACTIVE CATALYST, SLUR RYIN WATER;4-PIPERIDINAMINE,N,1-DIMETHYL;N,1-Dimethyl-4-piperidinamine;1-Methyl-4-(methylamino)piperidine;(1-Methylpiperidine-4-yl)methylamine;Methyl-(1-Methyl-piperidin-4-yl)-aMine
• CAS NO: 73579-08-5
• Molecular Formula: C₇H₁₆N₂
• Molecular Weight: 128.22
• EINECS: 277-542-1
• Mol File: 73579-08-5.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 53°C/10mmHg(lit.)
• Flash Point: 56°C
• Appearance: clear yellow liquid
• Density: 0,882 g/cm3
• Vapor Pressure: 2.06mmHg at 25°C
• Refractive Index: n20/D 1.4672(lit.)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-Methyl-4-(methylamino)piperidine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Methyl-4-(methylamino)piperidine(73579-08-5)
• EPA Substance Registry System: 1-Methyl-4-(methylamino)piperidine(73579-08-5)

Safety Data

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36/37/39
• RIDADR: 1993
• HazardClass: 3.2
• PackingGroup: III
• Hazardous Substances Data: 73579-08-5(Hazardous Substances Data)

Usage

Chemical Properties

clear yellow liquid

InChI:InChI=1/C7H16N2/c1-8-7-3-5-9(2)6-4-7/h7-8H,3-6H2,1-2H3/p+2

Upstream product

• 1445-73-4 1-Methyl-4-piperidone 
• 74-89-5 methylamine 
• 87571-98-0 4-chlorocarbonyl-4,9-dihydro-10H-thieno[3,4-b][1,5]benzodiazepin-10-one 

Downstream Products

• 217805-71-5 N-methyl-N'-4-(1-methylpiperidiyl)amido-3-formyl-4-hydroxybenzoic acid 
• 1026432-09-6 methyl-{1-[methyl-(1-methyl-piperidin-4-yl)-carbamoyl]-2-phenyl-ethyl}-carbamic acid tert-butyl ester 
• 864244-80-4 3-[4-(2-Fluoro-4-nitrophenoxy)pyridin-2-yl]-1-methyl-1-(1-methylpiperidin-4-yl)urea 
• 928038-23-7 1-(benzyloxycarbonyl)-N-(2-fluoro-4-{2-[3-methyl-3-(1-methylpiperidin-4-yl)ureido]pyridin-4-yloxy}phenyl)cyclopropanecarboxamide 
• 1025953-07-4 N-methyl-2-methylamino-N-{1-[methyl-(1-methyl-piperidin-4-yl)-carbamoyl]-2-phenyl-ethyl}-3-naphthalen-2-yl-propionamide 
• 1027232-41-2 Methyl-[(R)-1-(methyl-{(R)-1-[methyl-(1-methyl-piperidin-4-yl)-carbamoyl]-2-phenyl-ethyl}-carbamoyl)-2-naphthalen-2-yl-ethyl]-carbamic acid tert-butyl ester 
• 502767-24-0 N-(3-chloro-4-methoxy-phenyl)-N'-cyclohexylmethyl-N-methyl-N-(1-methyl-piperidin-4-yl)-[1,3,5]triazine-2,4,6-triamine 
• 502767-26-2 N-(3-Chloro-4-methoxy-phenyl)-N'-methyl-N'-(1-methyl-piperidin-4-yl)-N-(1-propyl-butyl)-[1,3,5]triazine-2,4,6-triamine 

Relevant articles and documents

FUMARATE SALT OF (R)-3-(1-(2,3-DICHLORO-4-(PYRAZIN-2-YL)PHENYL)-2,2,2-TRIFLUOROETHYL)-1-METHYL-1-(1-METHYLPIPERIDIN-4-YL) UREA, METHODS OF PREPARATION, AND USES THEREOF

Provided are various embodiments relating to fumarate salt of (R)-3-(1-(2,3-dichloro-4-(pyrazin-2-yl)phenyl)-2,2,2-trifluoroethyl)-1-methyl-1-(1-methylpiperidin-4-yl) urea, and methods of producing and using the same to treat conditions and disorders associated with an increase of ghrelin level, such as food abuse, alcohol addiction, and other disorders (e.g., Prader-Willi syndrome). Also provided are various embodiments relating to crystalline HM04 free base, different crystalline forms of HM04 fumarate salt, and methods of producing the same.

Tetracyclic benzimidazole derivatives and combinatorial libraries thereof

The present invention relates to novel tetracyclic benzimidazole derivative compounds of the following formula: wherein R1to R10have the meanings described in here. The invention further relates to combinatorial libraries containing two or more such compounds, as well as methods of preparing tetracyclic benzimidazole derivative compounds.

Benzenesulfonamide derivatives and their use as MEK inhibitors

Benzenesulfonamides of formula (I), in which W is OR1, NR2OR1, NRARB, NR2NRARB, or NR2(CH2)2-4NRARBand the other variables as defined in the claims, are inhibitors of MEK and are effective in the treatment of proliferative diseases, cancer, stroke, heart failure, xenograft rejection, arthritis, cystic fibrosis, hepatomegaly, cardiomegaly, Alzheimer's disease, complications of diabetes, septic shock, and viral infection.