73581-87-0

Basic information

• Product Name: (4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide
• CAS NO: 73581-87-0
• Molecular Formula: C₆H₁₁O₄P
• Molecular Weight: 178.1229
• Mol File: 73581-87-0.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 274.4°C at 760 mmHg
• Flash Point: 119.8°C
• Density: 1.39g/cm³
• Vapor Pressure: 0.00149mmHg at 25°C
• Refractive Index: 1.496
• CAS DataBase Reference: (4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide(CAS DataBase Reference)
• NIST Chemistry Reference: (4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide(73581-87-0)
• EPA Substance Registry System: (4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide(73581-87-0)

Safety Data

• Hazardous Substances Data: 73581-87-0(Hazardous Substances Data)

Usage

Description

(4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide is a complex organophosphorus compound featuring a cyclopentane ring fused to a 1,3,2-dioxaphosphinin-2-ol moiety. It is characterized by the presence of a phosphorus atom and an oxygen atom within its structure, making it a phosphinic acid derivative. This unique structural composition suggests potential applications in organic synthesis and medicinal chemistry, although further research is required to fully explore its properties and uses.

Uses

Used in Organic Synthesis:
(4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide is used as a key intermediate for the synthesis of various complex organic molecules. Its unique structure allows for versatile chemical reactions, making it a valuable building block in the creation of novel compounds with potential applications in various fields.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, (4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide is used as a starting material for the development of new pharmaceuticals. Its distinctive structural features may contribute to the design of innovative drugs with improved efficacy and selectivity, targeting specific biological pathways.
Used in Pharmaceutical Research:
(4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide is employed as a research tool in the pharmaceutical industry to study its interactions with various biological targets. Understanding these interactions can lead to the discovery of new therapeutic agents and the advancement of drug design strategies.
Used in Chemical Reagent Development:
(4aR,7aS)hexahydrocyclopenta[d][1,3,2]dioxaphosphinin-2-ol 2-oxide is also used as a reagent in the development of new chemical processes and methodologies. Its unique properties may enable the creation of more efficient and selective synthetic routes, contributing to the advancement of chemical research and technology.

Upstream product

• 52429-85-3 3-((4aS,7aR)-2-Oxo-hexahydro-2λ⁵-cyclopenta[1,3,2]dioxaphosphinin-2-yloxy)-butan-2-one 
• 68755-19-1 trans-2-hydroxycyclopentanemethanol cyclic phosphoric acid phenyl ester 
• 1883-85-8 trans-2-(hydroxymethyl)cyclopentanol 
• 68755-19-1 (4aR,7aR)-2-Phenoxy-hexahydro-cyclopenta[1,3,2]dioxaphosphinine 2-oxide 
• 75-64-9 tert-butylamine 

Relevant articles and documents

Influence of Phosphorus Derivatization on the Conformational Behavior of Model Compounds for 3',5'-xylo-cAMP Studied by 1H NMR Spectroscopy

A number of epimeric pairs of 3-X-3-Y-cis-2,4-dioxa-3-phosphabicyclononanes (2, X = OCH3, Y = O; 3, X = OCH3, Y = S; 4, X = OPh, Y = O; 5, X = OPh, Y = S; 6, X = Cl, Y = O; 7, X = Cl, Y = S; 8, X = N(CH3)2, Y = O; 9, X = N(CH3)2, Y = S; 10, X = Ss

Thermochemical Identification of the Structural Factors Responsible for the Thermodynamic Instability of 3',5'-Cyclic Nucleotides

The enthalpies of hydrolysis of several cyclic phosphate diesters which can be considered to be structural analogues of the trans-fused trimethylene phosphate-ribofuranoside ring system of adenosine 3',5'-cyclic phosphate have been determined by microcalo