7359-14-0

Basic information

• Product Name: 5-IODO-O-VANILLIN
• Synonyms: 5-IODO-2-VANILLIN;5-IODO-O-VANILLIN;2-HYDROXY-3-METHOXY-5-IODOBENZALDEHYDE;2-HYDROXY-5-IODO-3-METHOXYBENZALDEHYDE
• CAS NO: 7359-14-0
• Molecular Formula: C₈H₇IO₃
• Molecular Weight: 278.04
• Product Categories: Aromatic Aldehydes & Derivatives (substituted)
• Mol File: 7359-14-0.mol
• Article Data: 5

Chemical Properties

• Melting Point: 127-130°C
• Boiling Point: 326.5°C at 760 mmHg
• Flash Point: 151.3°C
• Appearance: /
• Density: 1.909g/cm³
• Vapor Pressure: 0.000113mmHg at 25°C
• Refractive Index: 1.671
• CAS DataBase Reference: 5-IODO-O-VANILLIN(CAS DataBase Reference)
• NIST Chemistry Reference: 5-IODO-O-VANILLIN(7359-14-0)
• EPA Substance Registry System: 5-IODO-O-VANILLIN(7359-14-0)

Safety Data

• Statements: 36/37/38
• Safety Statements: 26-36
• Hazardous Substances Data: 7359-14-0(Hazardous Substances Data)

Usage

Uses

is used in preparation of α,β-unsaturated amide compounds having anti-cancer activity.

InChI:InChI=1/C8H7IO3/c1-12-7-3-6(9)2-5(4-10)8(7)11/h2-4,11H,1H3

Upstream product

• 148-53-8 3-methoxy-2-hydroxybenzaldehyde 

Downstream Products

• 7413-12-9 4-Iod-2-methoxy-5-(2-nitro-vinyl)-phenol 
• 7396-70-5 2-Acetoxy-1-diacetoxymethyl-3-methoxy-5-jod-benzol 
• 7429-59-6 (2-Formyl-4-jod-6-methoxy-phenoxy)essigsaeure-ethylester 
• 7396-76-1 1,2-Bis-(5-jod-2-hydroxy-3-methoxy-benzylidenamino)-ethan 
• 7396-68-1 5-Iod-o-vanillal-anilin 
• 7396-66-9 5-iodo-2,3-dimethoxybenzaldehyde 
• 7396-78-3 5-Iod-2,3-dimethoxy-1-(2-nitro-vinyl)-benzol 
• 7396-71-6 2,3-Dimethoxy-5-iod-1-phenyliminomethyl-benzol 
• 727375-40-8 2-hydroxy-3-methoxy-5-(2-(trimethylsilyl)ethynyl)benzaldehyde 
• 1159568-05-4 6-[4-(2-Hydroxy-5-iodo-3-methoxy-benzyl)-piperazin-1-yl]-3H-pyrimidin-4-one 
• 1204351-38-1 2-(2-formyl-4-iodo-6-methoxyphenoxy)acetonitrile 
• 1415971-59-3 N-(5-(4-cyanophenyl)-3-methoxysalicylidene)-phenylene-1,2-diamine 
• 156398-61-7 (E)-2-(4-hydroxy-3-methoxyphenyl)-5-(3-hydroxyprop-1-enyl)-7-methoxybenzofuran 
• 530-22-3 egonol 

Relevant articles and documents

Function of Fimsbactin B as an Acinetobacter-Selective Antibiotic Delivery Vehicle

The ability of fimsbactin B, a natural siderophore of Acinetobacter baumannii, to function as an antibiotic delivery vehicle was investigated by synthesizing three structurally diversified fimsbactin B-cefaclor conjugates. Their antimicrobial activities w

a, ? UNSATURATED AMIDE COMPOUND

The present invention provides an α,β-unsaturated amide compound or a pharmaceutically acceptable salt or the like thereof having anticancer activity and the like represented by the following formula (I): [wherein, "A" represents optionally substituted heterocyclic diyl, R1 represents hydrogen atom or optionally substituted lower alkyl, R2 represents optionally substituted aryl, optionally substituted cycloalkyl, optionally substituted aliphatic heterocyclic group or optionally substituted aromatic heterocyclic group, X represents -O-, -S-, -SO2-, -NRX1- (wherein, RX1 represents hydrogen atom or lower alkyl), -CHRX2- (wherein, RX2 represents hydrogen atom or hydroxy), -CH=CH-, -CO- or -NH-CO-, and n1 and n2 are the same or different, and each represents 0 or 1].

New short synthesis of (5)-2,3-dimethoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl] -5-iodobenzamide: Dopamine D2 receptor

A new short and highly efficient synthesis of (5)-2,3-dimethoxy-N[(1-ethyl- 2-pyrrolidinyl)methyl]-5-iodobenzamide (epidepride, 1) from 3-methoxy- salicylaldehyde (o-vanillin, 2) and 3-methoxysalicyclic acid (6) was achieved by employing a new iodination