73591-81-8

Basic information

• Product Name: 5-methyl-1-(3,5-di-O-benzoyl-α-D-ribofuranosyl)-3-methoxycarbonylpyridinium chloride
• CAS NO: 73591-81-8
• Molecular Weight: 527.958
• Mol File: 73591-81-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-methyl-1-(3,5-di-O-benzoyl-α-D-ribofuranosyl)-3-methoxycarbonylpyridinium chloride(CAS DataBase Reference)
• NIST Chemistry Reference: 5-methyl-1-(3,5-di-O-benzoyl-α-D-ribofuranosyl)-3-methoxycarbonylpyridinium chloride(73591-81-8)
• EPA Substance Registry System: 5-methyl-1-(3,5-di-O-benzoyl-α-D-ribofuranosyl)-3-methoxycarbonylpyridinium chloride(73591-81-8)

Safety Data

• Hazardous Substances Data: 73591-81-8(Hazardous Substances Data)

Upstream product

• 73611-06-0 3,5-di-O-benzoyl-β-D-ribofuranosyl chloride 
• 29681-45-6 5-methylnicotinic acid methyl ester 
• 3222-49-9 5-methylnicotinic acid 
• 42972-46-3 1-(5-methylpyridin-3-yl)ethanone 

Relevant articles and documents

STEREOSPECIFIC SYNTHESIS OF A NOVEL SERIES OF PYRIDINE NUCLEOSIDES

Condensation of 3,5-di-O-benzoyl-β-D-ribofuranosyl chloride severally with 3-acetyl-5-alkylpyridines, 5-alkyl-3-methoxycarbonylpyridines (alkyl= Me, Et, Pr, and iPr), 5-isopropylnicotinamide, and 3,5-diacetylpyridine bis(ethylene acetal) in acetonitrile at -5 deg C gave the corresponding 1-(3,5-di-O-benzoyl-β-D-ribofuranosyl)-3,5-disubstituted pyridinium chlorides in excellent yield (90percent).From the reaction of a series of 2,3-O-isopropylidene-β-D-ribofuranosyl halides with 3-acetyl-5-methyl-pyridine at room temperature, the α-nucleosides were obtained.