73608-71-6

Basic information

• Product Name: 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone
• Synonyms: 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone
• CAS NO: 73608-71-6
• Molecular Weight: 307.39
• Mol File: 73608-71-6.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone(73608-71-6)
• EPA Substance Registry System: 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone(73608-71-6)

Safety Data

• Hazardous Substances Data: 73608-71-6(Hazardous Substances Data)

Upstream product

• 421-20-5 Methyl fluorosulfonate 
• 81835-67-8 3,3-ethylenedioxy-4-methyl-N-(3,4,5-trimethoxybenzylidene)pentylamine 
• 86-81-7 3,4,5-trimethoxy-benzaldehyde 
• 72189-37-8 4-methyl-1-methylamino-3-pentanone hydrochloride 
• 81835-76-9 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone ethylene acetal 
• 74611-11-3 5-carbethoxy-1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone 
• 81835-73-6 3,3-dimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone 
• 74-88-4 methyl iodide 
• 32830-98-1 1-chloro-4-methyl-pentan-3-one 
• 81835-65-6 1-amino-4-methyl-3-pentanone ethylene acetal 
• 81835-61-2 4-methyl-1-phthalimido-3-pentanone 
• 81835-63-4 4-methyl-1-phthalimido-3-pentanone ethylene acetal 
• 81835-70-3 3,3-dimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidone ethylene acetal 
• 73608-65-8 N(trimethoxy-3,4,5 benzylidene) methylamine 

Downstream Products

• 58780-84-0 1,3,3-trimethyl-2-(3,4,5-trimethoxyphenyl)-4-methylenepiperidine 

Relevant articles and documents

Determination of Rotational Barriers of Carbon-Carbon Bonds in 2-Arylpiperidines

Carbon-carbon sp3-sp2 rotational barriers of 3,3-dimethyl-2-(3,4,5-trimethoxyphenyl)-4-piperidones and treir ethylene ketals have been evaluated using nmr techniques.The conformation of 1 hydrochloride has been studied by NOE determinations.Values found for the hydrochlorides of the title compounds are discussed in terms of equilibria with free bases and nitrogen inversion.

MANNICH CYCLIZATION INVOLVING THE α-POSITION OF KETALS: SYNTHESIS OF 2-ARYL-4-PIPERIDONES AND 2-ARYL-3-ACYLPYRROLIDINES

A new method for the preparation of 2-aryl-4-piperidones and 2-aryl-3-acylpyrrolidines based on the acid-induced intramolecular cyclization between an iminium salt and the α-position of a ketal group is reported.

A Reinvestigation of the Stevens Rearrangement of 1,3,4-Trimethyl-1-(3,4,5-trimethoxybenzyl)-1,2,5,6-tetrahydropyridinium Chloride

1,3,3-Trimethyl-2-(3,4,5-trimethoxyphenyl)-4-methylenepiperidine (XI) is prepared in an unambiguous way which involves the Reformatsky reaction followed by ethanolysis on the N-(3,4,5-trimethoxybenzylidene)methylamine, later treatment of the resulting ami