736140-73-1

Basic information

• Product Name: (2E)-3-(3-chlorophenyl)-1-pyrrol-1-yl-2-propen-1-one
• Synonyms: (2E)-3-(3-chlorophenyl)-1-pyrrol-1-yl-2-propen-1-one
• CAS NO: 736140-73-1
• Molecular Weight: 231.681
• Mol File: 736140-73-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2E)-3-(3-chlorophenyl)-1-pyrrol-1-yl-2-propen-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: (2E)-3-(3-chlorophenyl)-1-pyrrol-1-yl-2-propen-1-one(736140-73-1)
• EPA Substance Registry System: (2E)-3-(3-chlorophenyl)-1-pyrrol-1-yl-2-propen-1-one(736140-73-1)

Safety Data

• Hazardous Substances Data: 736140-73-1(Hazardous Substances Data)

Upstream product

• 587-04-2 m-Chlorobenzaldehyde 
• 627546-31-0 1-(1H-pyrrol-1-yl)-2-(triphenylphosphoranylidene)ethanone 

Relevant articles and documents

Catalytic asymmetric epoxidation of α,β-unsaturated N-acylpyrroles as monodentate and activated ester equivalent acceptors

Catalytic asymmetric epoxidation of α,β-unsaturated N-acylpyrroles as monodentate and activated ester equivalent acceptors is described. A Sm(O-i-Pr)3/(R)-H8-BINOL complex promoted the epoxidation reaction to afford products in high yield (up to quant) and high enantiomeric excess (up to >99.5% ee). Reaction proceeded smoothly using cumene hydroperoxide (CMHP) with low explosive hazard, and completed within 0.2-0.5 h with 5 mol % catalyst. Catalyst loading was successfully reduced to as little as 0.02 mol %. The N-acylpyrrole properties as well as efficient synthesis of α,β-unsaturated N-acylpyrroles are also described.